C122009
L-Cystine
99%
Synonym(s):
(R,R)-3,3′-Dithiobis(2-aminopropionic acid)
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About This Item
Linear Formula:
[-SCH2CH(NH2)CO2H]2
CAS Number:
Molecular Weight:
240.30
EC Number:
200-296-3
UNSPSC Code:
12352209
MDL number:
Beilstein/REAXYS Number:
1728094
assay
99%
optical activity
[α]20/D −217.8°, c = 1 in 1 M HCl
mp
>240 °C (dec.) (lit.)
SMILES string
N[C@@H](CSSC[C@H](N)C(O)=O)C(O)=O
InChI
1S/C6H12N2O4S2/c7-3(5(9)10)1-13-14-2-4(8)6(11)12/h3-4H,1-2,7-8H2,(H,9,10)(H,11,12)/t3-,4-/m0/s1
InChI key
LEVWYRKDKASIDU-IMJSIDKUSA-N
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Storage Class
13 - Non Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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Philip J Hogg
Nature reviews. Cancer, 13(6), 425-431 (2013-05-11)
Protein action in nature is generally controlled by the amount of protein produced and by chemical modification of the protein, and both are often perturbed in cancer. The amino acid side chains and the peptide and disulphide bonds that bind
Martijn J Wilmer et al.
American journal of physiology. Renal physiology, 299(5), F905-F916 (2010-09-10)
Renal proximal tubules are highly sensitive to ischemic and toxic insults and are affected in diverse genetic disorders, of which nephropathic cystinosis is the most common. The disease is caused by mutations in the CTNS gene, encoding the lysosomal cystine
Anne C Conibear et al.
The Journal of biological chemistry, 288(15), 10830-10840 (2013-02-23)
θ-Defensins are ribosomally synthesized cyclic peptides found in the leukocytes of some primate species and have promising applications as antimicrobial agents and scaffolds for peptide drugs. The cyclic cystine ladder motif, comprising a cyclic peptide backbone and three parallel disulfide
Jan Lewerenz et al.
Antioxidants & redox signaling, 18(5), 522-555 (2012-06-07)
The antiporter system x(c)(-) imports the amino acid cystine, the oxidized form of cysteine, into cells with a 1:1 counter-transport of glutamate. It is composed of a light chain, xCT, and a heavy chain, 4F2 heavy chain (4F2hc), and, thus
The x(c)- cystine/glutamate antiporter: a potential target for therapy of cancer and other diseases.
Maisie Lo et al.
Journal of cellular physiology, 215(3), 593-602 (2008-01-09)
The x(c) (-) cystine/glutamate antiporter is a major plasma membrane transporter for the cellular uptake of cystine in exchange for intracellular glutamate. Its main functions in the body are mediation of cellular cystine uptake for synthesis of glutathione essential for
Global Trade Item Number
| SKU | GTIN |
|---|---|
| W267708-5KG-K | 04061837806988 |
| 1A00900-25MG | 04065269096726 |
| 8212430250 | 04022536476605 |
| 59932-1ML | 04061832644738 |
| W267708-10KG-K | 04061837806957 |
| W267708-1KG-K | 04061837806964 |
| W267708-25KG-K | 04061837806971 |
| W267708-SAMPLE-K | 04061837515910 |
| 8212431000 | 04022536476612 |
| M26615-100G | 04061834045939 |
| M26615-500G | 04061834045946 |
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