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H1529

Sigma-Aldrich

8-Hydroxypyrene-1,3,6-trisulfonic acid trisodium salt

≥96%

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Synonym(s):
HPTS, Pyranine, Solvent Green 7, Trisodium 8-hydroxypyrene-1,3,6-trisulfonate
Empirical Formula (Hill Notation):
C16H7Na3O10S3
CAS Number:
Molecular Weight:
524.39
Beilstein:
4107272
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22

description

Handling storage condition: Sightly light sensitive

Quality Level

Assay

≥96%

mp

>300 °C (lit.)

fluorescence

λex 454 nm; λem 511 nm (pH 9.1)
λex 454 nm; λem 520 nm in H2O

SMILES string

[Na+].[Na+].[Na+].Oc1cc(c2ccc3c(cc(c4ccc1c2c34)S([O-])(=O)=O)S([O-])(=O)=O)S([O-])(=O)=O

InChI

1S/C16H10O10S3.3Na/c17-11-5-12(27(18,19)20)8-3-4-10-14(29(24,25)26)6-13(28(21,22)23)9-2-1-7(11)15(8)16(9)10;;;/h1-6,17H,(H,18,19,20)(H,21,22,23)(H,24,25,26);;;/q;3*+1/p-3

InChI key

KXXXUIKPSVVSAW-UHFFFAOYSA-K

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Application

8-Hydroxypyrene-1,3,6-trisulfonic acid trisodium salt (HPTS) can be used to prepare:
  • Extruded fluorescent plastic indicator film for the detection of gaseous and dissolved CO2.
  • Highly fluorescent waterborne polyurethane (WPU) matrix which is used as a pH sensing indicator.
  • Positive (p-type) semiconducting polymeric gels via free radical cross-linking co-polymerization.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

481.3 °F

Flash Point(C)

249.6 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Highly CO2 sensitive extruded fluorescent plastic indicator film based on HPTS.
Mills A and Yusufu D
Analyst, 141(3), 999-1008 (2016)
Aaron C Schmidt et al.
Advanced science (Weinheim, Baden-Wurttemberg, Germany), 7(8), 1903697-1903697 (2020-04-25)
Trimethylamine (TMA) is a metabolite overtly present in patients suffering from trimethylaminuria (TMAU), a rare genetic disorder characterized by a strong "fishy" body odor. To date, no approved pharmacological treatment to sequester excess TMA on the skin of patients exists.
Zhiping Zhou et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 25(33), 7558-7566 (2005-08-19)
Auditory information is conveyed into the CNS via the spiral ganglion neurons, cells that possess distinctive electrophysiological properties that vary according to their cochlear innervation. Neurons from the base of the cochlea fire action potentials with shorter latencies and durations
8-Hydroxypyrene-1, 3, 6-trisulfonic acid trisodium salt (HPTS) based high fluorescent, pH stimuli waterborne polyurethane coatings.
Kumar R, et al.
Polymer, 136(3), 157-165 (2018)
Simone Graf et al.
Scientific reports, 9(1), 4766-4766 (2019-03-20)
The cytochrome bo3 quinol oxidase from Vitreoscilla (vbo3) catalyses oxidation of ubiquinol and reduction of O2 to H2O. Data from earlier studies suggested that the free energy released in this reaction is used to pump sodium ions instead of protons

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