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Merck
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W329703

L-Leucine

99%, FG

Synonym(s):

(S)-2-Amino-4-methylpentanoic acid

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About This Item

Linear Formula:
(CH3)2CHCH2CH(NH2)CO2H
CAS Number:
61-90-5
Molecular Weight:
131.17
FEMA Number:
3297
Council of Europe no.:
10482
UNSPSC Code:
12164502
PubChem Substance ID:
24901619
Flavis number:
17.012
EC Number:
200-522-0
NACRES:
NA.21
MDL number:
MFCD00002617
Beilstein/REAXYS Number:
1721722
Organoleptic:
odorless
Grade:
FG, Kosher
Biological source:
plant
Agency:
meets purity specifications of JECFA
Food allergen:
no known allergens

Key Documents

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biological source

plant

Quality Level

300, 400

grade

FG, Kosher

agency

meets purity specifications of JECFA

reg. compliance

EU Regulation 1334/2008 & 178/2002, FDA 21 CFR 172.320, FDA 21 CFR 172.804

assay

99%

optical activity

[α]20/D +15.5°, c = 2 in 6 M HCl

mp

>300 °C (lit.)

application(s)

flavors and fragrances

documentation

see Safety & Documentation for available documents

food allergen

no known allergens

organoleptic

odorless

SMILES string

CC(C)C[C@H](N)C(O)=O

InChI

1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1

InChI key

ROHFNLRQFUQHCH-YFKPBYRVSA-N

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General description

L-Leucine is a branched-chain amino acid mainly found in whey proteins.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
SHBT4918
SHBT3899
SHBT1871
SHBT1101
SHBP5749

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Whey proteins in the regulation of food intake and satiety.
Luhovyy BL, et al.
Journal of the American College of Nutrition, 26(6), 704S-712S (2007)
Irena Roci et al.
Cell reports, 26(7), 1691-1700 (2019-02-14)
Alterations in cell-cycle regulation and cellular metabolism are associated with cancer transformation, and enzymes active in the committed cell-cycle phase may represent vulnerabilities of cancer cells. Here, we map metabolic events in the G1 and SG2M phases by combining cell
Gaetano Santulli et al.
The Journal of clinical investigation, 125(5), 1968-1978 (2015-04-07)
The type 2 ryanodine receptor (RyR2) is a Ca2+ release channel on the endoplasmic reticulum (ER) of several types of cells, including cardiomyocytes and pancreatic β cells. In cardiomyocytes, RyR2-dependent Ca2+ release is critical for excitation-contraction coupling; however, a functional
T Yoshimasa et al.
The Journal of clinical investigation, 69(3), 643-650 (1982-03-01)
To elucidate the physiological and pathophysiological significance of methionine- and leucine-enkephalin (Met-and Leu-enkephalin, respectively) in human sympathoadrenal system, the contents of these peptides in normal human sympathetic nervous system, adrenal medulla, and pheochromocytomas were determined by specific radioimmunoassays combined with
Marika Leenders et al.
Nutrition reviews, 69(11), 675-689 (2011-10-28)
Amino acids function as precursors for de novo protein synthesis. In addition, however, they play a key role as nutritional signals that regulate multiple cellular processes. There is ample in vitro and in vivo evidence showing that muscle tissue responds
View All Related Papers

Related Content

Global Trade Item Number

SKUGTIN
W329703-1KG-K04061835566921
W329703-100G-K04061837529603
W329703-5KG-K04061834397557
W329703-SAMPLE-K04061834356301

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