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Merck
CN

W502715

Succinic acid

natural

Synonym(s):

Butanedioic acid

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About This Item

Linear Formula:
HOOCCH2CH2COOH
CAS Number:
110-15-6
Molecular Weight:
118.09
UNSPSC Code:
12164502
Flavis number:
8.024
PubChem Substance ID:
24902010
EC Number:
203-740-4
Beilstein/REAXYS Number:
1754069
MDL number:
MFCD00002789
Organoleptic:
acidic; sour
Grade:
Kosher, natural
Food allergen:
no known allergens

Key Documents

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grade

Kosher, natural

assay

99.0-100.5% (by NaOH, titration)

form

crystalline powder

bp

235 °C (lit.)

mp

184-186 °C (lit.), 185-190 °C

solubility

water: 83 g/L at 25 °C

density

1.564 g/cm3 at 15 °C

cation traces

As: ≤3.0 ppm, Cd: ≤1.0 ppm, Hg: ≤1.0 ppm, Pb: ≤2.0 ppm

application(s)

flavors and fragrances

documentation

see Safety & Documentation for available documents

food allergen

no known allergens

organoleptic

acidic; sour

SMILES string

OC(=O)CCC(O)=O

InChI

1S/C4H6O4/c5-3(6)1-2-4(7)8/h1-2H2,(H,5,6)(H,7,8)

InChI key

KDYFGRWQOYBRFD-UHFFFAOYSA-N

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pictograms

Corrosion
GHS05

signalword

Danger

hcodes

H318

Hazard Classifications

Eye Dam. 1

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
MKBD8023
01096EJ
05001LC

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G M Tannahill et al.
Nature, 496(7444), 238-242 (2013-03-29)
Macrophages activated by the Gram-negative bacterial product lipopolysaccharide switch their core metabolism from oxidative phosphorylation to glycolysis. Here we show that inhibition of glycolysis with 2-deoxyglucose suppresses lipopolysaccharide-induced interleukin-1β but not tumour-necrosis factor-α in mouse macrophages. A comprehensive metabolic map
Susan Jahn et al.
Biochimica et biophysica acta, 1833(12), 2879-2889 (2013-07-28)
To investigate a possible role of the nitrogen-PTS (PTS(Ntr)) in controlling carbon metabolism, we determined the growth of Escherichia coli LJ110 and of isogenic derivatives, mutated in components of the PTS(Ntr), on different carbon sources. The PTS(Ntr) is a set
José Manuel Otero et al.
PloS one, 8(1), e54144-e54144 (2013-01-26)
Saccharomyces cerevisiae is the most well characterized eukaryote, the preferred microbial cell factory for the largest industrial biotechnology product (bioethanol), and a robust commerically compatible scaffold to be exploitted for diverse chemical production. Succinic acid is a highly sought after
James H Marden et al.
Evolution; international journal of organic evolution, 67(4), 1105-1115 (2013-04-05)
Oxygen conductance to the tissues determines aerobic metabolic performance in most eukaryotes but has cost/benefit tradeoffs. Here we examine in lowland populations of a butterfly a genetic polymorphism affecting oxygen conductance via the hypoxia-inducible factor (HIF) pathway, which senses intracellular
Yun Chen et al.
Current opinion in biotechnology, 24(6), 965-972 (2013-04-02)
Bio-based production of chemical building blocks from renewable resources is an attractive alternative to petroleum-based platform chemicals. Metabolic pathway and strain engineering is the key element in constructing robust microbial chemical factories within the constraints of cost effective production. Here
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Global Trade Item Number

SKUGTIN
W502715-SAMPLE-K04061833421888

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