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Merck
CN

ALD00004

Li-Yu t-Butyl Quinoline

95%

Synonym(s):

3,4-Dihydro-7-tert-butyl-2,5-dimethyl-2H-pyrano[2,3-b]quinoline

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About This Item

Empirical Formula (Hill Notation):
C18H23NO
Molecular Weight:
269.38
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352005
MDL number:
Assay:
95%
Form:
solid
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InChI

1S/C18H23NO/c1-11-6-8-14-12(2)15-10-13(18(3,4)5)7-9-16(15)19-17(14)20-11/h7,9-11H,6,8H2,1-5H3

SMILES string

CC1=C2C(OC(C)CC2)=NC3=C1C=C(C(C)(C)C)C=C3

InChI key

HGKGTNXPFXRVQB-UHFFFAOYSA-N

assay

95%

form

solid

reaction suitability

reaction type: C-C Bond Formation, reagent type: catalyst, reagent type: ligand
reaction type: C-H Activation

mp

202-207 °C

Quality Level

Application

Ligand is optimal for gamma C-H functionalization of aliphatic acids through Pd-catalyzed C-H activation. The Yu group has demonstrated a variety of transformations, such as olefination, carbonylation, and arylation.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Related Content

Yu program focuses on efficient C–H bond activation for drug synthesis, using simple starting materials.

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