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Merck
CN

ALD01784

N-(tert-butyl)-2-methoxypyridin-3-amine

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About This Item

MDL number:
UNSPSC Code:
12352116
PubChem Substance ID:
NACRES:
NA.22
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InChI

1S/C10H16N2O/c1-10(2,3)12-8-6-5-7-11-9(8)13-4/h5-7,12H,1-4H3

InChI key

KNFHUHWGLSSVFV-UHFFFAOYSA-N

SMILES string

CC(C)(C)NC1=CC=CN=C1OC

form

liquid

storage temp.

2-8°C

Application

Traditionally challenging to access, this hindered amine provides a chemically differentiated building block for organic synthesis and medicinal chemistry, specifically for preparation of drug candidates containing hindered amine motifs. Additionally, this and over 80 other sterically hindered secondary amines in the Sigma-Aldrich portfolio provide structurally distinct screening compounds. Screen several through Aldrich Market Select. This hindered amine was accessed via a recent publication reported by Baran and coworkers using an innovative hydroamination method.

pictograms

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Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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