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Merck
CN

L040031

Cap A

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UNSPSC Code:
12352200
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type

for DNA synthesis

Quality Segment

product line

Proligo Reagents

concentration

97.0-119.0 g/L (acetic anhydride, titration)

color

clear colorlessto brownish

General description

Cap A solution consists of acetic anhydrideanhydride, lutidine, and tetrahydrofuran (THF).

Application

Cap A solution is used after the phosphoramidite reaction/coupling step.

Biochem/physiol Actions

Cap A solution aborts chains bearing unreacted 5′ hydroxyl groups due to failure of reaction with activated phosphoramidite (typically, 1 to 2% of growing oligonucleotide chains in each synthesis cycle). These unreacted 5′ hydroxyl groups are capped with an acetyl group and thus rendered unreactive for subsequent synthesis steps.


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signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

supp_hazards

存储类别

3 - Flammable liquids

wgk

WGK 3



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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