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Merck
CN

O3132

Oxibendazole

~98%

Synonym(s):

Methyl (5-propoxy-1H-benzimidazol-2-yl)carbamate

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About This Item

Empirical Formula (Hill Notation):
C12H15N3O3
CAS Number:
Molecular Weight:
249.27
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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Assay

~98%

Quality Level

storage temp.

2-8°C

SMILES string

CCCOc1ccc2[nH]c(NC(=O)OC)nc2c1

InChI

1S/C12H15N3O3/c1-3-6-18-8-4-5-9-10(7-8)14-11(13-9)15-12(16)17-2/h4-5,7H,3,6H2,1-2H3,(H2,13,14,15,16)

InChI key

RAOCRURYZCVHMG-UHFFFAOYSA-N

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Biochem/physiol Actions

Anthelminthic

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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G W Lubega et al.
Biochemical pharmacology, 41(1), 93-101 (1991-01-01)
The low- and high-affinity binding of tritiated benzimidazole anthelmintics (mebendazole and oxibendazole) to tubulin-containing supernatants derived from unembryonated eggs, third stage larvae or adult worms of thiabendazole-susceptible and -resistant strains of Haemonchus contortus were examined and compared. The displacement of
D W Gottschall et al.
Veterinary parasitology, 64(1-2), 83-93 (1996-08-01)
Groups of male swine were administered a single oral dose of 14C-oxibendazole in a gelatin capsule at a level of 15 mg kg-1 bodyweight and killed after 10 h, 24 h, and 7 days withdrawal. Combustion analysis indicated that liver
M R Chapman et al.
Veterinary parasitology, 66(3-4), 205-212 (1996-11-15)
Three fecal egg count reduction assays (FECR) and one critical trial were performed to determine the efficacy of pyrantel pamoate (PP) at 6.6 mg base kg-1 on a well managed stud farm in Louisiana where a loss of efficacy was
E T Lyons et al.
Parasitology research, 103(2), 287-291 (2008-05-13)
Horse foals on five farms in Central Kentucky were used in field studies in 2007 evaluating activity of paste formulations of four compounds (fenbendazole-FBZ, ivermectin-IVM, oxibendazole-OBZ, and pyrantel pamoate-PRT) against internal parasites with emphasis on ascarids (Parascaris equorum). It has
P A Overgaauw et al.
The Veterinary quarterly, 20(2), 69-72 (1998-05-01)
The anthelmintic efficacy and safety of the oxibendazole component in a combination oxibendazole-niclosamide paste were investigated in dogs and cats and in litters of pups with naturally acquired nematode infections. A single dose of 15 mg oxibendazole/kg body weight given

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