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O3132

Sigma-Aldrich

Oxibendazole

~98%

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Synonym(s):
Methyl (5-propoxy-1H-benzimidazol-2-yl)carbamate
Empirical Formula (Hill Notation):
C12H15N3O3
CAS Number:
20559-55-1
Molecular Weight:
249.27
EC Number:
243-877-7
MDL number:
MFCD00133728
PubChem Substance ID:
57654481
NACRES:
NA.22

Assay

~98%

Quality Level

100

storage temp.

2-8°C

SMILES string

CCCOc1ccc2[nH]c(NC(=O)OC)nc2c1

InChI

1S/C12H15N3O3/c1-3-6-18-8-4-5-9-10(7-8)14-11(13-9)15-12(16)17-2/h4-5,7H,3,6H2,1-2H3,(H2,13,14,15,16)

InChI key

RAOCRURYZCVHMG-UHFFFAOYSA-N

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Related Categories

Biochem/physiol Actions

Anthelminthic

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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G W Lubega et al.
Biochemical pharmacology, 41(1), 93-101 (1991-01-01)
The low- and high-affinity binding of tritiated benzimidazole anthelmintics (mebendazole and oxibendazole) to tubulin-containing supernatants derived from unembryonated eggs, third stage larvae or adult worms of thiabendazole-susceptible and -resistant strains of Haemonchus contortus were examined and compared. The displacement of
R P Herd et al.
Veterinary parasitology, 48(1-4), 229-240 (1993-06-01)
Environmental consequences of treating horses with recommended dosages of ivermectin paste were studied in two controlled experiments with 29 horses in Ohio. In 1988, dung dispersal rates were measured by changes in dry weight over time of 48 copromes (300
F F Franssen et al.
Antimicrobial agents and chemotherapy, 39(6), 1265-1268 (1995-06-01)
In the light of the increased incidence of human Encephalitozoon infections and the absence of an established treatment protocol, a simple in vitro testing method to compare activities of drugs against Encephalitozoon cuniculi was developed. With this in vitro method
C R Reinemeyer et al.
Journal of the American Veterinary Medical Association, 206(11), 1710-1715 (1995-06-01)
Forty 11- to 12-week-old helminth-naive Beagles were categorized by sex and weight and randomly assigned to 4 treatment groups (group 1, ivermectin/pyrantel pamoate; group 2, milbemycin oxime; group 3, untreated control; group 4, diethylcarbamazine/oxibendazole). Each pup was inoculated PO with
S E Bunch
The Veterinary clinics of North America. Small animal practice, 23(3), 659-670 (1993-05-01)
Historical aspects, mechanisms, and treatment of hepatotoxicity associated with pharmacologic agents in dogs and cats are discussed. All agents that cause clinically relevant drug-induced hepatotoxicity have been reviewed within the last 5 years; therefore, only selected drugs that more recently
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