QBD10201
Biotin-dPEG®3-MAL
Synonym(s):
Polyethylene glycol
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About This Item
Empirical Formula (Hill Notation):
C27H43N5O8S
Molecular Weight:
597.72
UNSPSC Code:
51171641
PubChem Substance ID:
NACRES:
NA.22
assay
>90%
form
solid or viscous liquid
reaction suitability
reagent type: cross-linking reagent
reaction type: Biotinylations
reactivity: thiol reactive, reagent type: linker
polymer architecture
shape: linear
functionality: monofunctional
shipped in
ambient
storage temp.
−20°C
SMILES string
O=C(NCCCOCCOCCOCCCNC(CCCCC1C2NC(NC2CS1)=O)=O)CCN3C(C=CC3=O)=O
InChI
1S/C27H43N5O8S/c33-22(6-2-1-5-21-26-20(19-41-21)30-27(37)31-26)28-10-3-13-38-15-17-40-18-16-39-14-4-11-29-23(34)9-12-32-24(35)7-8-25(32)36/h7-8,20-21,26H,1-6,9-19H2,(H,28,33)(H,29,34)(H2,30,31,37)
InChI key
QCEXTKIIGXBNCN-UHFFFAOYSA-N
Application
Biotin-dPEG®3-MAL can be used as a cross-linking reagent in biotinylation reaction.
Features and Benefits
Biotin-dPEG®3-MAL takes advantage of the well-known, specific Michael reaction between a maleimide group and a free sulfhydryl to allow site-specific biotin labeling of molecules in aqueous media within the pH range of 6.5 – 7.5. The single molecular weight dPEG® spacer (24.9 Å) provide precise spacing between the biotin moiety and the labeled molecule. The dPEG® spacer imparts water solubility to the labeled molecule while reducing immunogenicity, aggregation, and precipitation of labeled biomolecules or other labeled compounds.
Legal Information
Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Amanda R Smith et al.
Retrovirology, 16(1), 28-28 (2019-10-24)
PIE12-trimer is a highly potent D-peptide HIV-1 entry inhibitor that broadly targets group M isolates. It specifically binds the three identical conserved hydrophobic pockets at the base of the gp41 N-trimer with sub-femtomolar affinity. This extremely high affinity for the transiently
Global Trade Item Number
| SKU | GTIN |
|---|---|
| QBD10201-50MG | 04061832876924 |