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Merck
CN

QBD10931

m-dPEG®36-MAL

>95% (HPLC)

Synonym(s):

mPEG36-MAL, mPEG-maleimide, mPEG1500-maleimide, mPEG36-maleimide

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About This Item

Empirical Formula (Hill Notation):
C80H154N2O39
Molecular Weight:
1768.07
UNSPSC Code:
12352200
NACRES:
NA.22
MDL number:
MFCD21363231
Assay:
>95% (HPLC)
Form:
solid or viscous liquid

Key Documents

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SMILES string

N1(C(=O)C=CC1=O)CCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC

InChI

1S/C80H154N2O39/c1-86-8-9-88-12-13-90-16-17-92-20-21-94-24-25-96-28-29-98-32-33-100-36-37-102-40-41-104-44-45-106-48-49-108-52-53-110-56-57-112-60-61-114-64-65-116-68-69-118-72-73-120-76-77-121-75-74-119-71-70-117-67-66-115-63-62-113-59-58-111-55-54-109-5

InChI key

LVODUJCWJYAVKH-UHFFFAOYSA-N

assay

>95% (HPLC)

form

solid or viscous liquid

reaction suitability

reaction type: Pegylations

polymer architecture

shape: linear
functionality: monofunctional

shipped in

ambient

storage temp.

−20°C

Features and Benefits

m-dPEG36-MAL is a methyl-terminated, thiol-reactive, monodispersed PEGylation product designed for surface and biomolecule modification. This single molecular weight PEG reagent has a discrete chain length of 116 atoms spanning a distance of 132.4 Å. One end of the molecule terminates in a maleimido-propionic acid group, which is conjugated to the dPEG spacer by an amide bond. The maleimide moiety reacts with sulfhydryls to form a thioether bond. dPEG36 is a monodisperse equivalent of the polymeric PEG1500. Modification of cysteine residues on peptides, proteins, and other sulfhydryl-containing molecules with m-dPEG36-MAL will increase hydrophilicity and decrease immunogenicity.

Legal Information

Products Protected under U.S. Patent #s 7,888,536 & 8,637,711 and European Patent #s 1,594,440 & 2,750,681
dPEG is a registered trademark of Quanta BioDesign

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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