QBD11471
MAL-dPEG®12-Tris(m-dPEG®24)3
>95% (HPLC)
别名:
Branched Maleimide-PEG-m, Branched mPEG-maleimide, MAL-NH-PEG600-Tris(mPEG1000)3, MAL-PEG12-Tris(m-PEG24)3
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关于此项目
经验公式（希尔记法）:
C194H378N6O94
分子量:
4299.06
NACRES:
NA.22
UNSPSC Code:
12352106
assay
>95% (HPLC)
form
solid or viscous liquid
reaction suitability
reaction type: Pegylations
polymer architecture
functionality: monofunctional
shipped in
ambient
storage temp.
−20°C
Features and Benefits
MAL-dPEG12-Tris(m-dPEG24)3 is a thiol-reactive, methyl-terminated, four-arm monodispersed PEG product designed to modulate biodistribution of conjugates. Tris forms the core of the molecule. Three equal-length methyl-terminated long arms plus one maleimido-terminated short arm extend from the tris core. From the maleimido olefin to the terminal methyl groups on each arm, the end-to-end length of this product is 127 atoms with an average distance of 103.7 Å. The amphiphilic PEG imparts hydrophilicity to conjugates, reduces or eliminates the conjugates′ antigenicity, and increases the hydrodynamic volume of conjugated molecules. Applications for this product include eradicating renal clearance, maintaining in vivo circulation for more extended periods, and suppressing immune responses to conjugates.
Legal Information
Products Protected under U.S. Patent #s 7,888,536 & 8,637,711 and European Patent #s 1,594,440 & 2,750,681
dPEG is a registered trademark of Quanta BioDesign
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable