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R1757

D-(−)-Ribose

Name: <SC>D</SC>-(−)-Ribose
Brand: ALDRICH

98%

Synonym(s):

D-Ribose

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About This Item

Empirical Formula (Hill Notation):

C₅H₁₀O₅

CAS Number:

50-69-1

Molecular Weight:

150.13

UNSPSC Code:

12352201

NACRES:

NA.22

PubChem Substance ID:

24899349

EC Number:

200-059-4

Beilstein/REAXYS Number:

1723081

MDL number:

MFCD00135453

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Properties

Quality Level

100

assay

98%

optical activity

[α]20/D −19.7°, c = 4 in H₂O

mp

88-92 °C (lit.)

SMILES string

OC[C@@H](O)[C@@H](O)[C@@H](O)C([H])=O

InChI

1S/C5H10O5/c6-1-3(8)5(10)4(9)2-7/h1,3-5,7-10H,2H2/t3-,4+,5-/m0/s1

InChI key

PYMYPHUHKUWMLA-LMVFSUKVSA-N

Description

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

涉药品监管产品

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Translating the concept of peptide labeling with 5-deoxy-5-[18F]fluororibose into preclinical practice: 18F-labeling of Siglec-9 peptide for PET imaging of inflammation.

Xiang-Guo Li et al.

Chemical communications (Cambridge, England), 49(35), 3682-3684 (2013-03-29)

Peptide glycosylation with 5-deoxy-5-[(18)F]fluororibose was translated into preclinical settings. The novel (18)F-labeled Siglec-9 peptide was produced using an automated synthesis procedure. The (18)F-labeled Siglec-9 peptide showed favorable binding in the animal model of inflammation in vivo.

The biolabile 2'-O-pivaloyloxymethyl modification in an RNA helix: an NMR solution structure.

Carine Baraguey et al.

Organic & biomolecular chemistry, 11(16), 2638-2647 (2013-03-05)

The pivaloyloxymethyl (PivOM) group is a biolabile 2'-O-ribose protection that is under development in a prodrug-based approach for siRNA applications. Besides an expected cellular uptake, nucleic acid sequences carrying PivOM showed also increased nuclease resistance and, in most cases, an

Poly(A)-specific ribonuclease (PARN): an allosterically regulated, processive and mRNA cap-interacting deadenylase.

Anders Virtanen et al.

Critical reviews in biochemistry and molecular biology, 48(2), 192-209 (2013-03-19)

Deadenylation of eukaryotic mRNA is a mechanism critical for mRNA function by influencing mRNA turnover and efficiency of protein synthesis. Here, we review poly(A)-specific ribonuclease (PARN), which is one of the biochemically best characterized deadenylases. PARN is unique among the

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Global Trade Item Number

SKU	GTIN
R1757-10G-A	04061836694487
R1757-100G-A	04061836694470
R1757-25G-A	04061836694494