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Merck
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541602C

Avanti

Soy Extract Polar

Avanti Research™ - A Croda Brand

Synonym(s):

Soybean Polar Lipid Extract

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About This Item

CAS Number:
8030-76-0
MDL number:
MFCD00133396
NACRES:
NA.25
UNSPSC Code:
12352211

Key Documents

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Product Name

Soy Extract Polar, Avanti Research™ - A Croda Brand

form

chloroform solution

packaging

pkg of 2 × 20 mL (541602C-1g)
pkg of 1 × 4 mL (541602C-100mg)
pkg of 5 × 4 mL (541602C-500mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand

concentration

25 mg/mL (541602C-100mg)
25 mg/mL (541602C-1g)
25 mg/mL (541602C-500mg)

lipid type

lipid extracts

shipped in

dry ice

storage temp.

−20°C

Application

Soy Extract Polar has been used:
  • in the preparation of liposomes for forester resonance energy transfer (FRET)-based assay
  • along with 1,2-dioleoyl-sn-glycero-3-phospho-L-serine (sodium salt) (DOPS) to mimic the cell membrane inner leaflet and for the preparation of giant unilamellar vesicle (GUV) connected to a multilamellar vesicle (MLV)
  • in liposome preparation for the generation of GUV-MLV reservoirs

Biochem/physiol Actions

Soy Extract Polar (SPE) is useful in the preparation of unilamellar liposomes and also nanotube networks. The hockey-puck-like structure of the SPE provides a native lipid membrane for various studies.

General description

Polar Lipid Extract is derived from the total lipid extract by precipitation with acetone followed by extraction of the acetone insoluble material with diethyl ether.
The Soy Extract Polar (SPE) comprises majorly phosphatidylcholine (45.7%), phosphatidylethanolamine (PE 22.1%) and phosphatidylinositol (PI, 18.4%). It also has phosphatidic acid (PA, 6.9%) and a mixture of other unknown lipids (6.9%). Soybean is the natural source of soy polar extract.

Packaging

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (541602C-1g)
5 mL Clear Glass Sealed Ampule (541602C-100mg)
5 mL Clear Glass Sealed Ampule (541602C-500mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash

Regulatory Information

危险化学品
易制毒化学品（2类）
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A cell-penetrating scorpion toxin enables mode-specific modulation of TRPA1 and pain
King JV, et al.
Cell, 178(6), 1362-1374 (2019)
Membrane remodeling of giant vesicles in response to localized calcium ion gradients
Doosti BA
Journal of Visualized Experiments, e57789-e57789 (2018)
Short-chain alcohols promote accelerated membrane distention in a dynamic liposome model of exocytosis
Wittenberg NJ, et al.
Langmuir, 24(6), 2637-2642 (2008)
Cryo-EM structures of the mammalian endo-lysosomal TRPML1 channel elucidate the combined regulation mechanism
Zhang S, et al.
Protein & cell, 8(11), 834-847 (2017)
Johan Berg et al.
Biochimica et biophysica acta. Bioenergetics, 1861(2), 148116-148116 (2019-11-17)
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