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About This Item
Empirical Formula (Hill Notation):
C48H74 BF2N4 O10P
CAS Number:
Molecular Weight:
946.90
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
Product Name
TopFluor™ TMR PA, Avanti Research™ - A Croda Brand 810240P, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (810240P-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 810240P
shipped in
dry ice
storage temp.
−20°C
Biochem/physiol Actions
Phosphatidic acid (PA) is a signaling molecule that is synthesized in the endoplasmic reticulum (ER). It is transported to the mitochondrial outer membrane to stimulate mitofusin (Mfn)-mediated fusion. PA is a major intermediate metabolite involved in the synthesis of membrane glycerophospholipids, which include phosphatidylcholine (PC), phosphatidylserine (PS), phosphatidylethanolamine (PE), and phosphatidylserine (PS).
General description
Phosphatidic acid (PA) is a diacyl-glycerophospholipid that consists of a glycerol and an alcohol moiety, having two fatty acids and a phosphate group esterified at positions 1, 2, and 3, respectively.
Packaging
5 mL Amber Glass Screw Cap Vial (810240P-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
TopFluor is a trademark of Avanti Polar Lipids, LLC
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
No data available
flash_point_c
No data available
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Phosphatidic acid and cardiolipin coordinate mitochondrial dynamics
Brain Lipids in Synaptic Function and Neurological Disease: Clues to Innovative Therapeutic Strategies for Brain Disorders, 28(1), 67-76 (2015)
Phosphatidic acid and cardiolipin coordinate mitochondrial dynamics
Multifunctional Systems for Combined Delivery Biosensing and Diagnostics, 28(1), 67-76 (2020)
Shoichiro Kameoka et al.
Trends in cell biology, 28(1), 67-76 (2017-09-16)
Membrane organelles comprise both proteins and lipids. Remodeling of these membrane structures is controlled by interactions between specific proteins and lipids. Mitochondrial structure and function depend on regulated fusion and the division of both the outer and inner membranes. Here
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