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About This Item
Empirical Formula (Hill Notation):
C50H76 BF2N4 O10P
Molecular Weight:
972.94
UNSPSC Code:
12352211
NACRES:
NA.25
Product Name
TopFluor™ TMR PE, Avanti Research™ - A Croda Brand 810241C
Assay
>99% (TLC)
form
liquid
packaging
pkg of 1 × 1 mL (810241C-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 810241C
concentration
1 mg/mL (810241C-1mg)
shipped in
dry ice
storage temp.
−20°C
General description
TopFluor™ TMR PE is an acyl-chain-modified fluorescent phospholipid. L-α-Phosphatidylethanolamine (PE) is a membrane phospholipid and is the second most abundant phospholipid in animals, plants and yeast. It is the major lipid in bacteria.
Application
TopFluor™ TMR PE is suitable to use as a component of vesicle and a donor-acceptor for fluorescence quenching. It is also suitable for the formation of lipid membrane.
Biochem/physiol Actions
L-α-Phosphatidylethanolamine (PE) is essential for maintaining the structural integrity of membranes. TopFluor™ TMR PE is useful for cellular labelling.
Packaging
5 mL Amber Glass Screw Cap Vial (810241C-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
TopFluor is a trademark of Avanti Polar Lipids, LLC
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
Target Organs
Central nervous system
WGK
WGK 3
Regulatory Information
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Single-molecule analysis of phospholipid scrambling
by TMEM16F
Watanabe R, et al.
Proceedings of the National Academy of Sciences of the USA (2018)
Phosphatidylserine and phosphatidylethanolamine in mammalian cells: two metabolically related aminophospholipids
Vance JE
Journal of Lipid Research, 49(7), 1377-1387 (2008)
Ann C Kimble-Hill et al.
The journal of physical chemistry. B, 122(35), 8404-8415 (2018-06-08)
Phosphatidylinositol (PI) lipids are necessary for many cellular signaling pathways of membrane associated proteins, such as angiomotin (Amot). The Amot family regulates cellular polarity, growth, and migration. Given the low concentration of PI lipids in these membranes, it is likely
Formation and function of phosphatidylserine and phosphatidylethanolamine in mammalian cells
Vance JE and Tasseva G
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1831(3), 543-554 (2013)
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