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Merck
CN

810242C

Avanti

TopFluor™ TMR PS

Avanti Research™ - A Croda Brand

Synonym(s):

1-oleoyl-2-(6-((4,4-difluoro-1,3-dimethyl-5-(4-methoxyphenyl)-4-bora-3α,4α-diaza-s-indacene-2-propionyl)amino)hexanoyl)-sn-glycero-3- phospho-L-serine (ammonium salt)

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About This Item

Empirical Formula (Hill Notation):
C51H79 BF2N5 O12P
CAS Number:
2260795-43-3
Molecular Weight:
1033.98
MDL number:
MFCD00133433
NACRES:
NA.25
UNSPSC Code:
12352211

Key Documents

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Product Name

TopFluor™ TMR PS, Avanti Research™ - A Croda Brand 810242C

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mL (810242C-1mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 810242C

concentration

1 mg/mL (810242C-1mg)

shipped in

dry ice

storage temp.

−20°C

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General description

Phosphoserine is a phosphoamino acid that is most abundant in the eukaryotic phosphoproteome. Phosphoserine is synthesized post-translationally as it is not encoded in the genetic code.

Biochem/physiol Actions

Phosphoserine (PS) is a metabolic precursor for serine. In some methanogenic archaea, PS is utilised to incorporate cysteine into proteins.

Packaging

5 mL Amber Glass Screw Cap Vial (810242C-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC
TopFluor is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

target_organs

Central nervous system, Liver,Kidney

wgk

WGK 3

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

flash_point_f

does not flash

flash_point_c

does not flash

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

Regulatory Information

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Daniel T Rogerson et al.
Nature chemical biology, 11(7), 496-503 (2015-06-02)
Serine phosphorylation is a key post-translational modification that regulates diverse biological processes. Powerful analytical methods have identified thousands of phosphorylation sites, but many of their functions remain to be deciphered. A key to understanding the function of protein phosphorylation is
Hee-Sung Park et al.
Science (New York, N.Y.), 333(6046), 1151-1154 (2011-08-27)
O-Phosphoserine (Sep), the most abundant phosphoamino acid in the eukaryotic phosphoproteome, is not encoded in the genetic code, but synthesized posttranslationally. Here, we present an engineered system for specific cotranslational Sep incorporation (directed by UAG) into any desired position in

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