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About This Item
Empirical Formula (Hill Notation):
C51H79 BF2N5 O12P
CAS Number:
Molecular Weight:
1033.98
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
Product Name
TopFluor™ TMR PS, Avanti Research™ - A Croda Brand 810242C
Assay
>99% (TLC)
form
liquid
packaging
pkg of 1 × 1 mL (810242C-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 810242C
concentration
1 mg/mL (810242C-1mg)
shipped in
dry ice
storage temp.
−20°C
General description
Phosphoserine is a phosphoamino acid that is most abundant in the eukaryotic phosphoproteome. Phosphoserine is synthesized post-translationally as it is not encoded in the genetic code.
Biochem/physiol Actions
Phosphoserine (PS) is a metabolic precursor for serine. In some methanogenic archaea, PS is utilised to incorporate cysteine into proteins.
Packaging
5 mL Amber Glass Screw Cap Vial (810242C-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
TopFluor is a trademark of Avanti Polar Lipids, LLC
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
Target Organs
Central nervous system, Liver,Kidney
WGK
WGK 3
Regulatory Information
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Daniel T Rogerson et al.
Nature chemical biology, 11(7), 496-503 (2015-06-02)
Serine phosphorylation is a key post-translational modification that regulates diverse biological processes. Powerful analytical methods have identified thousands of phosphorylation sites, but many of their functions remain to be deciphered. A key to understanding the function of protein phosphorylation is
Hee-Sung Park et al.
Science (New York, N.Y.), 333(6046), 1151-1154 (2011-08-27)
O-Phosphoserine (Sep), the most abundant phosphoamino acid in the eukaryotic phosphoproteome, is not encoded in the genetic code, but synthesized posttranslationally. Here, we present an engineered system for specific cotranslational Sep incorporation (directed by UAG) into any desired position in
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