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About This Item
Empirical Formula (Hill Notation):
C54H92BF2N6O21P3
CAS Number:
Molecular Weight:
1303.07
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
Product Name
TopFluor™ TMR PI(4,5)P2, Avanti Research™ - A Croda Brand 810384P, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 50 μg (with stopper and crimp cap (810384P-50ug)), pkg of 2 × 50 μg (with stopper and crimp cap (810384P-100ug))
manufacturer/tradename
Avanti Research™ - A Croda Brand 810384P
shipped in
dry ice
storage temp.
−20°C
General description
Phosphatidylinositol 4,5-bisphosphate/(PI(4,5)P2 or PIP2) is one of the major constituent of the inner leaflet of the plasma membrane, especially in eukaryotic cells. It is an important phosphoinositide phosphate species in mammalian cells.
Biochem/physiol Actions
Phosphatidylinositol 4,5-bisphosphate/(PI(4,5)P2 or PIP2) actively participates in numerous cellular signaling pathways. It acts as a precursor of phosphatidylinositol (3,4,5)-trisphosphate (PI(3,4,5)P3). It helps in the assembly of several viruses, like human immunodeficiency virus 1 (HIV1).
Packaging
2 mL Amber Serum Vial with Stopper and Crimp Cap (810384P-100ug)
2 mL Amber Serum Vial with Stopper and Crimp Cap (810384P-50ug)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
TopFluor is a trademark of Avanti Polar Lipids, LLC
Storage Class
11 - Combustible Solids
flash_point_f
No data available
flash_point_c
No data available
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Multivalent cation-bridged PI (4, 5) P2 clusters form at very low concentrations
Wen Y, et al.
Biophysical Journal, 114(11), 2630-2639 (2018)
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