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Merck
CN

840055P

Avanti

Liver PC

Avanti Research™ - A Croda Brand

Synonym(s):

L-α-phosphatidylcholine (Liver, Bovine)

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About This Item

CAS Number:
475662-36-3
MDL number:
MFCD00674330
UNSPSC Code:
12352211
NACRES:
NA.25

Key Documents

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Product Name

Liver PC, Avanti Research™ - A Croda Brand 840055P, powder

InChI

1S/C44H84NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-43(46)50-40-42(41-52-54(48,49)51-39-38-45(3,4)5)53-44(47)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h15,17,21,23,42H,6-14,16,18-20,22,24-41H2,1-5H3/b17-15-,23-21-/t42-/m1/s1

InChI key

FORFDCPQKJHEBF-VPUSDGANSA-N

SMILES string

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O)=O

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 25 mg (840055P-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 840055P

lipid type

phosphoglycerides
phospholipids

shipped in

dry ice

storage temp.

−20°C

Application

Liver PC is suitable for use:
  • as a standard for quantitation of tumor derived lipids by thin layer chromatography
  • in the preparation of liposomes to mimic mammalian membranes
  • in lipid vesicle preparation to study intravesicular transfer of α-tocopherol fluorescent derivative (NBD-Toc)

Biochem/physiol Actions

Phosphatidylcholine (PC) plays a key role in the synthesis of second messenger and signaling molecules like diacyl glycerol, lysophosphatidic acid, phosphatidic acid and arachidonic acid. Liver PC has a saturated to unsaturated fatty acid ratio of 0.91.

General description

Phosphatidylcholine (PC) has two fatty acid chains attached to a head group. Generally, PC has saturated fatty acid in the sn-1 position and unsaturated fatty acid in the sn-2 position. It has a quaternary ammonium group and a phosphate moiety in the head group, existing as a zwitterion in a wide range of pH.

Packaging

5 mL Clear Glass Sealed Ampule (840055P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

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Noncovalently and covalently bound lipid on the receptor for immunoglobulin E
Kinet JP, et al.
Biochemistry, 24(25), 7342-7348 (1985)
Liposomes with diverse compositions are protected during desiccation by LEA proteins from Artemia franciscana and trehalose
Moore DS, et al.
Biochimica et Biophysica Acta - Biomembranes, 1858(1), 104-115 (2016)
Essentials of Medical Biochemistry: With Clinical Cases (2011)
Effect of bilayer phospholipid composition and curvature on ligand transfer by the alpha-tocopherol transfer protein
Zhang WX, et al.
Lipids, 44(7), 631-631 (2009)
The Kennedy pathway?de novo synthesis of phosphatidylethanolamine and phosphatidylcholine
Gibellini F and Smith TK
IUBMB Life, 62(6), 414-428 (2010)
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