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Merck
CN

840101P

Avanti

Egg PA

Avanti Research™ - A Croda Brand

Synonym(s):

L-α-phosphatidic acid (Egg, Chicken) (sodium salt)

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About This Item

CAS Number:
383907-53-7
MDL number:
MFCD00672609
UNSPSC Code:
12352211
NACRES:
NA.25

Key Documents

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Product Name

Egg PA, Avanti Research™ - A Croda Brand

SMILES string

[H][C@@](COP([O-])(O)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]

InChI

1S/C37H71O8P.Na/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-37(39)45-35(34-44-46(40,41)42)33-43-36(38)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2;/h17-18,35H,3-16,19-34H2,1-2H3,(H2,40,41,42);/q;+1/p-1/b18-17-;/t35-;/m1./s1

InChI key

PPYXMAJBOKWTQX-RYRMQHSSSA-M

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 g (840101P-1g)
pkg of 2 × 100 mg (840101P-200mg)
pkg of 5 × 100 mg (840101P-500mg)
pkg of 1 × 25 mg (840101P-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand

lipid type

phosphoglycerides

shipped in

dry ice

storage temp.

−20°C

Application

Egg PA is suitable for use:
  • in the preparation of reconstituted high density lipoprotein (rHDL) along with serum amyloid A (SAA)
  • as negatively charged lipid in the preparation of giant unilamellar vesicles
  • in the preparation of liposomes

Biochem/physiol Actions

Phosphatidic acid (PA) is involved in the synthesis of phosphatidylcholine, phosphatidylethanolamine, phosphatidylinositol, phosphatidylserine and cardiolipin. PA functions as a signaling molecule.

General description

Phosphatidic acid is a simple and basic glycerophospholipid. It is an ester of glycerol with two long chain fatty acids at C1 and C2 position and phosphoric acid at C3 position. PA is synthesized by the hydrolytic action of phospholipase D on glycerophospholipids.

Packaging

5 mL Clear Glass Sealed Ampule (840101P-200mg)
5 mL Clear Glass Sealed Ampule (840101P-25mg)
5 mL Clear Glass Sealed Ampule (840101P-500mg)
60 mL Amber Wide Mouth Screw Cap Glass Bottle (840101P-1g)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

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Certificates of Analysis (COA)

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Biochemistry of Lipids, Lipoproteins and Membranes (1996)
Hepatitis B virus X protein induces size-selective membrane permeabilization through interaction with cardiolipin
You DG, et al.
Biochimica et Biophysica Acta - Biomembranes, 1861(4), 729-737 (2019)
Effects of lipid composition on the structural properties of human serum amyloid A in reconstituted high-density lipoprotein particles
Takase H, et al.
Chemistry and Physics of Lipids, 221, 8-14 (2019)
Muscle and Exercise Physiology (2018)
Membrane permeabilization by trypanosome lytic factor, a cytolytic human high density lipoprotein
Harrington JM, et al.
The Journal of Biological Chemistry, 284(20), 13505-13512 (2009)
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