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Merck
CN

840497C

Avanti

16:0-18:2 PG

Avanti Research™ - A Croda Brand

Synonym(s):

1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-(1′racglycerol) (sodium salt); PG(16:0/18:2(9Z,12Z))

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About This Item

Empirical Formula (Hill Notation):
C40H74O10PNa
CAS Number:
322647-44-9
Molecular Weight:
768.97
MDL number:
MFCD00674295
UNSPSC Code:
51191904
NACRES:
NA.25

Key Documents

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Product Name

16:0-18:2 PG, 1-palmitoyl-2-linoleoyl-sn-glycero-3-phospho-(1′-rac-glycerol) (sodium salt), chloroform

SMILES string

[Na+].[P](=O)([O-])(OC[C@H](OC(=O)CCCCCCC\C=C/C\C=C/CCCCC)COC(=O)CCCCCCCCCCCCCCC)OCC(O)CO

InChI

1S/C40H75O10P.Na/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-40(44)50-38(36-49-51(45,46)48-34-37(42)33-41)35-47-39(43)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2;/h11,13,17-18,37-38,41-42H,3-10,12,14-16,19-36H2,1-2H3,(H,45,46);/q;+1/p-1/b13-11-,18-17-;/t37?,38-;/m1./s1

InChI key

JBOGSUDWCXWRFD-YBBFZHODSA-M

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (840497C-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 840497C

concentration

10 mg/mL (840497C-25mg)

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

Application

16:0-18:2 PG or 1-palmitoyl-2-linoleoyl-sn-glycero-3-phospho-(1′-rac-glycerol) (sodium salt) might be used as a phospholipid standard to identify phospholipid classes in phosphorus assay. It might also be used in liposomes to study its effect on the proliferation of mouse keratinocytes, in vitro.

Biochem/physiol Actions

Phosphatidylglycerol (PG) is useful in preparing nanoliposomes.

General description

16:0-18:2 PG or 1-palmitoyl-2-linoleoyl-sn-glycero-3-phospho-(1′-rac-glycerol) is a sodium salt of glycerophospholipid, with substitution of palmitic acid, linolenic acid and phospho-rac-(1-glycerol) at the sn-1, sn-2 and sn-3 positions respectively, in the glycerol backbone.
Phosphatidylglycerol (PG) is an anionic lipid, enriched in several bacterial membranes. It is present in animal tissues, mainly in the lung surfactant.

Packaging

5 mL Clear Glass Sealed Ampule (840497C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system

wgk

WGK 3

Regulatory Information

易制毒化学品（2类）
危险化学品
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Pulmonary Surfactant Trafficking and Homeostasis
Lung Epithelial Biology in the Pathogenesis of Pulmonary Disease, 117(5), 59-75 (2017)
Analysis of complex lipidomes
Medical Applications of Mass Spectrometry, 117(5), 223-249 (2008)
Nanoparticles: A novel approach to target tumors
Nano- and Microscale Drug Delivery Systems, 117(5), 113-129 (2017)
Anna M Russano et al.
The Journal of allergy and clinical immunology, 117(5), 1178-1184 (2006-05-06)
Evidences from mice and human beings indicate that gammadelta T cells could be relevant in recognition of stress-induced self and/or yet unidentified inhaled foreign antigens. Their specificity differs from classic MHC-restricted alphabeta T cells and involves the immunoglobulin-like structure of
Analysis of complex lipidomes
Medical Applications of Mass Spectrometry, 117(5), 223-249 (2008)
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