InChI key
FJXDNGDRHUDFST-XQYKCTAGSA-M
SMILES string
[H][C@@](COP([O-])(OCC(O)CO)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]
assay
>99% (TLC)
form
powder
packaging
pkg of 2 × 100 mg (841138P-200mg), pkg of 5 × 100 mg (841138P-500mg), pkg of 1 × 25 mg (841138P-25mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
lipid type
phosphoglycerides
shipped in
dry ice
storage temp.
−20°C
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General description
Phosphatidylglycerol (PG) is one of the major phospholipids in food and biological tissues. PG, structurally has two acyl chains esterified to a glycerol, which in turn is bonded to a headgroup structure that has phosphate and carries negative charge. PG is abundant in bacterial membranes and present in lower amounts in mammalian membranes. It is abundant in lung surfactant. PG is synthesized from cytidine phosphate-diacylglycerol (CDP-DAG).
Application
Egg PG has been used as anionic phospholipid substrate in serial protein misfolding cyclic amplification (sPMCA) reaction. It is also suitable for use in the preparation of large unilamellar vesicles (LUVs) and as a standard for liquid chromatography-mass spectrometric analysis (LC-MS).
Biochem/physiol Actions
Phosphatidylglycerol (PG) is an indicator of fetal lung maturity. It is a precursor for cardiolipin in animals. In plants, PG is present in thylakoid membranes and plays a central role in photosynthesis.
Packaging
5 mL Clear Glass Sealed Ampule (841138P-200mg)
5 mL Clear Glass Sealed Ampule (841138P-25mg)
5 mL Clear Glass Sealed Ampule (841138P-500mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class
11 - Combustible Solids
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Phosphatidylglycerol in amniotic fluid: comparison of an ?ultrasensitive? immunologic assay with TLC and enzymatic assay
Eisenbrey AB, et al.
American Journal of Bioscience, 91(3), 293-297 (1989)
Isolation of phosphatidylethanolamine as a solitary cofactor for prion formation in the absence of nucleic acids
Deleault NR, et al.
Proceedings of the National Academy of Sciences, 109(22), 8546-8551 (2012)
The
The Membranes of Cells, 911(3) (2016)
The
An Introduction to Biological Membranes: Composition, Structure and Function, 91(3) (2016)
Michael J Volles et al.
Journal of molecular biology, 366(5), 1510-1522 (2007-01-16)
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