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Merck
CN

850310P

Avanti

DOBAQ

Avanti Research™ - A Croda Brand

Synonym(s):

N-(4-carboxybenzyl)-N,N-dimethyl-2,3-bis(oleoyloxy)propan-1-aminium

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About This Item

Empirical Formula (Hill Notation):
C49H83NO6
CAS Number:
1360461-69-3
Molecular Weight:
782.19
MDL number:
MFCD28143623
UNSPSC Code:
12352211
NACRES:
NA.25

Key Documents

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Product Name

DOBAQ, Avanti Research™ - A Croda Brand 850310P, powder

InChI

1S/C49H83NO6/c1-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-47(51)55-43-46(42-50(3,4)41-44-37-39-45(40-38-44)49(53)54)56-48(52)36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-2/h19-22,37-40,46H,5-18,23-36,41-43H2,1-4H3/b21-19-,22-20-

InChI key

NYZTVPYNKWYMIW-WRBBJXAJSA-N

SMILES string

O=C(CCCCCCC/C=C\CCCCCCCC)OCC(OC(CCCCCCC/C=C\CCCCCCCC)=O)C[N+](C)(C)CC1=CC=C(C([O-])=O)C=C1

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 25 mg (850310P-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 850310P

lipid type

cationic lipids
headgroup modified lipids

shipped in

dry ice

storage temp.

−20°C

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General description

DOBAQ is a cationic lipids with a quaternary amine and unsaturated hydrocarbon chains. It is a pH-sensitive lipid.

Biochem/physiol Actions

N-(4-carboxybenzyl)-N,N-dimethyl2,3-bis(oleoyloxy)propan-1-aminium/DOBAQ displays pH-dependent ionization.

Packaging

5 mL Clear Glass Sealed Ampule (850310P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

Regulatory Information

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Liposomes in Analytical Methodologies (2016)
Lipid nanoparticles for delivery of messenger RNA to the back of the eye
Patel S, et al.
J. Controlled Release, 303, 91-100 (2019)

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