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Merck
CN

850325C

Avanti

10:0 PC

Avanti Research™ - A Croda Brand

Synonym(s):

1,2-dicapryl-sn-glycero-3-phosphocholine; PC(10:0/10:0)

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About This Item

Empirical Formula (Hill Notation):
C28H56NO8P
CAS Number:
3436-44-0
Molecular Weight:
565.72
MDL number:
MFCD00063538
UNSPSC Code:
51191904
NACRES:
NA.25

Key Documents

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Product Name

10:0 PC, 1,2-didecanoyl-sn-glycero-3-phosphocholine, chloroform

SMILES string

[P](=O)([O-])(OCC[N+](C)(C)C)OCC(OC(=O)CCCCCCCCC)COC(=O)CCCCCCCCC

InChI

1S/C28H56NO8P/c1-6-8-10-12-14-16-18-20-27(30)34-24-26(25-36-38(32,33)35-23-22-29(3,4)5)37-28(31)21-19-17-15-13-11-9-7-2/h26H,6-25H2,1-5H3

InChI key

MLKLDGSYMHFAOC-UHFFFAOYSA-N

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (850325C-25mg)
pkg of 2 × 4 mL (850325C-200mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 850325C

concentration

10 mg/mL (850325C-25mg)
25 mg/mL (850325C-200mg)

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

Application

10:0 PC is suitable for use in the preparation of lipid bilayer samples.

Biochem/physiol Actions

Phosphatidylcholine (PC) functions as a surfactant within the mucus to form a hydrophobic surface to inhibit bacterial penetrance. It is used to treat fat embolism. Phosphatidylcholine lowers the levels of cholesterol and triglycerides.

General description

Phosphatidylcholine (PC) is a strong bilayer-forming lipid. It the most common phospholipid in mammalian membranes. It is also an important component of the mucosal layer of the colon.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Packaging

5 mL Clear Glass Sealed Ampule (850325C-200mg)
5 mL Clear Glass Sealed Ampule (850325C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

target_organs

Liver,Kidney, Respiratory system

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash

Regulatory Information

危险化学品
易制毒化学品（2类）
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Tilt angle of a trans-membrane helix is determined by hydrophobic mismatch
Park SH and Opella SJ
Journal of molecular biology, 350(2), 310-318 (2005)
The Membranes of Cells (2016)
Integrative Medicine - E-Book (2017)
Efficacy of injections of phosphatidylcholine into fat deposits-a non-surgical alternative to liposuction in body-contouring
Karl GH, et al.
Indian journal of plastic surgery : official publication of the Association of Plastic Surgeons of India, 38(2), 119-119 (2005)
Chun-Cheih Chao et al.
Cell, 179(7), 1483-1498 (2019-12-10)
Metabolism has been shown to control peripheral immunity, but little is known about its role in central nervous system (CNS) inflammation. Through a combination of proteomic, metabolomic, transcriptomic, and perturbation studies, we found that sphingolipid metabolism in astrocytes triggers the

Articles

Critical Micelle Concentrations (CMCs) - Avanti Research™ Polar Lipids

The critical micelle concentration (CMC) can be approximately defined as the lipid monomer concentration at which appreciable amounts (>5% of total) of micellar aggregates first begin to appear in the equilibrium: nM1<=>Mn

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