产品名称
Facade™-EPC, 3α-hydroxy-7α,12α-di-(((2-(trimethylamino)ethyl)phosphoryl)ethyloxy)-cholane, powder
assay
>99% (TLC)
form
powder
mol wt
796.95 g/mol
packaging
pkg of 1 × 25 mg (850539P-25mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 850539P
shipped in
dry ice
storage temp.
−20°C
SMILES string
[H][C@@]12[C@]([C@](CC[C@@H](O)C3)(C)[C@]3([H])C[C@H]2OCCOP(OCC[N+](C)(C)C)([O-])=O)([H])C[C@H](OCCOP(OCC[N+](C)(C)C)([O-])=O)[C@@]4(C)[C@@]1([H])CC[C@@H]4[C@H](C)CCC
InChI
1S/C38H74N2O11P2/c1-11-12-28(2)31-13-14-32-36-33(27-35(38(31,32)4)47-22-24-51-53(44,45)49-20-18-40(8,9)10)37(3)16-15-30(41)25-29(37)26-34(36)46-21-23-50-52(42,43)48-19-17-39(5,6)7/h28-36,41H,11-27H2,1-10H3/t28-,29+,30-,31-,32+,33+,34-,35+,36+,37+,38-/m1/s
InChI key
RTNFJBQUBTXGHR-HECRFRQFSA-N
Application
Facade™-EPC has been used to produce bicelles for nuclear magnetic resonance (NMR) experiments. It may be used in crystallization of cytochrome P450 2B subfamily proteins, CYP2B35 and CYP2B37.
Biochem/physiol Actions
Facade™ is a mild rim forming surfactants, used in the synthesis of isotropic bicelles which prevents unfolding of soluble globular domains of large membrane proteins.
Facade™ EPC/FA-7 (3α-hydroxy-7α,12α-di-(((2-(trimethylamino)ethyl)phosphoryl)ethyloxy)-cholane) having phosphocholine groups helps in preparing smaller micelles than the facial amphiphiles (FAs) with nonionic sugar groups.
Packaging
5 mL Amber Glass Screw Cap Vial (850539P-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Facade is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids