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About This Item
Empirical Formula (Hill Notation):
C17H35NO6
CAS Number:
Molecular Weight:
349.46
MDL number:
UNSPSC Code:
12161902
NACRES:
NA.25
Product Name
MEGA-10, Avanti Research™ - A Croda Brand
SMILES string
OCC(O)C(O)C(O)C(O)CN(C)C(CCCCCCCCC)=O
InChI
1S/C17H35NO6/c1-3-4-5-6-7-8-9-10-15(22)18(2)11-13(20)16(23)17(24)14(21)12-19/h13-14,16-17,19-21,23-24H,3-12H2,1-2H3/t13-,14+,16+,17+/m0/s1
InChI key
UMWKZHPREXJQGR-XOSAIJSUSA-N
assay
>99% (TLC)
form
powder
mol wt
349.46 g/mol
packaging
pkg of 1 × 1 g (850542P-1G)
manufacturer/tradename
Avanti Research™ - A Croda Brand
shipped in
dry ice
storage temp.
−20°C
General description
Acyl-N-methylglucamide (MEGA) detergents are non-ionic detergents that provide a good starting point for your structural biology work. The hydrophilic head groups offer ample strength to extract proteins while still providing the capability to stabilize proteins in solution and promote crystal growth.
MEGA-10/N-decanoyl-N-methylglucamine is a longer carbon chain or a sugar-based surfactant. It is a member of the fatty acid glucamides family.
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Packaging
20 mL Clear Glass Screw Cap Vial (850542P-1G)
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Light scattering and fluorescence studies of non-ionic surfactant binary mixtures formed by MEGA-10 and C12E8
Molina-Bolivar JA and Ruiz CC
Journal of Molecular Liquids, 155(2-3), 96-102 (2010)
Influence of N-octanoyl-N-methylglucamine and N-decanoyl-N-methylglucamine on the kinetics and mechanism of Zn2+ ions electroreduction
Nieszporek J and Dagci K
Electrochimica Acta, 125, 473-481 (2014)
Matthew A Churchward et al.
Proteome science, 3(1), 5-5 (2005-06-09)
The analysis of hydrophobic membrane proteins by two-dimensional gel electrophoresis has long been hampered by the concept of inherent difficulty due to solubility issues. We have optimized extraction protocols by varying the detergent composition of the solubilization buffer with a
J M Hierrezuelo et al.
Langmuir : the ACS journal of surfaces and colloids, 20(24), 10419-10426 (2004-11-17)
The mixed micellization between the nonionic surfactant decanoyl-N-methylglucamide (MEGA-10) and the common sodium dodecyl sulfate (SDS) in aqueous solutions of 0.1 M NaCl was investigated by the fluorescence probe method. The critical micelle concentrations were determined by the pyrene 1:3
Jen-Hua Chuang et al.
Analytical biochemistry, 418(2), 298-300 (2011-08-30)
We studied the extraction and analysis of integral membrane proteins possessing hydrophobic and hydrophilic domains and found that a nonionic detergent called MEGA-10, used in lysis buffers, had a superior extraction effect compared to most conventional detergents. A sodium dodecyl
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