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About This Item
Empirical Formula (Hill Notation):
C14H31NO
CAS Number:
Molecular Weight:
229.40
MDL number:
UNSPSC Code:
12161902
NACRES:
NA.25
SMILES string
CCCCCCCCCCCC[N+](C)([O-])C
InChI
1S/C14H31NO/c1-4-5-6-7-8-9-10-11-12-13-14-15(2,3)16/h4-14H2,1-3H3
InChI key
SYELZBGXAIXKHU-UHFFFAOYSA-N
assay
>99% (TLC)
form
powder
mol wt
229.40 g/mol
packaging
pkg of 1 × 1 g (850545P-1g), pkg of 1 × 5 g (850545P-5g)
manufacturer/tradename
Avanti Research™ - A Croda Brand
technique(s)
electrophoresis: suitable
shipped in
dry ice
storage temp.
−20°C
General description
An optimized reverse micelle surfactant system has been developed for solution nuclear magnetic resonance studies of encapsulated proteins and nucleic acids dissolved in low viscosity fluids. Comprising the nonionic 1-decanoyl-rac-glycerol and the zwitterionic lauryldimethylamine-N-oxide (10MAG/LDAO), this mixture is shown to efficiently encapsulate a diverse set of proteins and nucleic acids. Chemical shift analyses of these systems show that high structural fidelity is achieved upon encapsulation.
LDAO (N,N-Dimethyldodecylamine N-oxide) is a zwitterionic detergent.
Application
LDAO is suitable to use in crystallization of membrane proteins. It is also suitable to enhance the detection of high molecular weight proteins.
Biochem/physiol Actions
LDAO can be used to disrupt phospholipid bilayer of cells.
Packaging
20 mL Clear Glass Screw Cap Vial (850545P-1g)
60 mL Amber Wide Mouth Glass Bottle with Screw Cap (850545P-5g)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2
Storage Class
11 - Combustible Solids
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Detergents for the stabilization and crystallization of membrane proteins
Prive GG
Methods, 41(4), 388-397 (2007)
MALDI mass spectrometry analysis of high molecular weight proteins from whole bacterial cells: pretreatment of samples with surfactants
Meetani MA and Voorhees KJ
Journal of the American Society For Mass Spectrometry, 16(9), 1422-1426 (2005)
Igor Dodevski et al.
Journal of the American Chemical Society, 136(9), 3465-3474 (2014-02-06)
An optimized reverse micelle surfactant system has been developed for solution nuclear magnetic resonance studies of encapsulated proteins and nucleic acids dissolved in low viscosity fluids. Comprising the nonionic 1-decanoyl-rac-glycerol and the zwitterionic lauryldimethylamine-N-oxide (10MAG/LDAO), this mixture is shown to
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