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Merck
CN

850802C

Avanti

18:0-18:2 PE

Avanti Research™ - A Croda Brand

Synonym(s):

1-octadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine; PE(18:0/18:2(9Z,12Z))

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About This Item

Empirical Formula (Hill Notation):
C41H78NO8P
CAS Number:
7266-53-7
Molecular Weight:
744.03
UNSPSC Code:
51191904
NACRES:
NA.25

Key Documents

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Product Name

18:0-18:2 PE, 1-stearoyl-2-linoleoyl-sn-glycero-3-phosphoethanolamine, chloroform

InChI

1S/C41H78NO8P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(43)47-37-39(38-49-51(45,46)48-36-35-42)50-41(44)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h12,14,18,20,39H,3-11,13,15-17,19,21-38,42H2,1-2H3,(H,45,46)/b14-12-,20-18-/t39-/m1/s1

InChI key

YDTWOEYVDRKKCR-KNERPIHHSA-N

SMILES string

[H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (850802C-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 850802C

concentration

10 mg/mL (850802C-25mg)

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

General description

Phosphatidylethanolamine (PE) is a membrane phospholipid and the types depend on the combination of free fatty acids on the α and β position.

Application

18:0-18:2 Phosphatidylethanolamine (PE) is suitable for use
  • in the preparation of monolayers
  • in the preparation of glucose-PE and lactose-PE as standards in multiple reaction monitoring (MRM) and mass spectrometry (MS/MS) analysis
  • as standards for mass spectrometry-electrospray ionization (MS-ESI)

Biochem/physiol Actions

Phosphatidylethanolamine (PE) is implicated in a numerous function like membrane fusion, cell cycle, autophagy, apoptosis, and cognitive function. 18:0-18:2 Phosphatidylethanolamine (PE) is one of the non-glycated PE in powdered milk. It is a beneficial source of fatty acid and plays an important role in immunological protection.

Packaging

5 mL Clear Glass Sealed Ampule (850802C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash

Regulatory Information

危险化学品
易制毒化学品（2类）
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Development of quantitation method for glycated aminophospholipids at the molecular species level in powdered milk and powdered buttermilk
Kodate A, et al.
Scientific Reports, 8(1), 8729-8729 (2018)
Ryo Takahashi et al.
Journal of proteomics, 166, 101-114 (2017-07-25)
Lipid hydroperoxide-mediated modifications of proteins are receiving increasing attention because of their possible involvement in various degenerative diseases. These biological effects are attributed to the ability of lipid peroxidation-derived aldehydes to react with the nucleophilic sites of proteins. Here we
A raft-associated species of phosphatidylethanolamine interacts with cholesterol comparably to sphingomyelin. A Langmuir-Blodgett monolayer study
Grzybek M, et al.
PLoS ONE, 4(3), e5053-e5053 (2009)
Diarachidonoylphosphoethanolamine induces necrosis/necroptosis of malignant pleural mesothelioma cells
Kaku Y, et al.
Cellular Signalling, 27(9), 1713-1719 (2015)

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