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CN

860055P

Avanti

Ganglioside GD1a

Avanti Research™ - A Croda Brand

Synonym(s):

Disialoganglioside-GD1a (porcine brain, diammonium salt)

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About This Item

Empirical Formula (Hill Notation):
C84H154N6O39
CAS Number:
12707-58-3
Molecular Weight:
1872.14
MDL number:
MFCD00130960
UNSPSC Code:
12352211
NACRES:
NA.25

Key Documents

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Product Name

Ganglioside GD1a, Avanti Research™ - A Croda Brand 860055P, powder

Assay

≥99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (860055P-1MG)
pkg of 1 × 5 mg (860055P-5MG)

manufacturer/tradename

Avanti Research™ - A Croda Brand 860055P

lipid type

lipid extracts
sphingolipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCCCCCC)=O)CO[C@H]1[C@H](O)C(O)[C@H](O[C@@H]2O[C@H](CO)[C@@H]([C@H](O[C@@]3(C([O-])=O)O[C@@H]([C@H](O)[C@H](O)CO)[C@@](NC(C)=O)([H])[C@@H](O)C3)[C@H]2O)O[C@@H]4O[C@@H]([C@@H]([C@H](O[C@@H]5O[C@H](CO)[C

InChI

1S/C86H152N4O39.2Na/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-51(100)50(90-60(105)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2)46-118-80-69(111)67(109)72(57(43-94)120-80)123-82-71(113)78(129-86(84(116)117)39-53(102)62(88-48(4)98)77(128-86)65(107)55(104)41-92)74(59(45-96)122-82)124-79-63(89-49(5)99)75(66(108)56(42-93)119-79)125-81-70(112)68(110)73(58(44-95)121-81)126-85(83(114)115)38-52(101)61(87-47(3)97)76(127-85)64(106)54(103)40-91;;/h34,36,50-59,61-82,91-96,100-104,106-113H,6-33,35,37-46H2,1-5H3,(H,87,97)(H,88,98)(H,89,99)(H,90,105)(H,114,115)(H,116,117);;/q;2*+1/p-2/b36-34+;;/t50-,51+,52?,53?,54-,55-,56?,57?,58?,59?,61+,62+,63?,64-,65-,66?,67?,68?,69?,70?,71?,72?,73?,74?,75?,76?,77?,78?,79?,80?,81?,82?,85?,86?;;/m0../s1

InChI key

CWLDKTAXQZEVQN-CUEXFKMESA-L

General description

Ganglioside GD1a is an anionic brain ganglioside. It is localized in the inner and outer membrane of nuclear envelope of the neuronal cells. GD1a contains a neutral tetrasaccharide core, with one or two sialic acid on the internal galactose. It also has an additional sialic acid on the non-reducing terminal of galactose.

Packaging

5 mL Amber Glass Screw Cap Vial (860055P-1MG)
5 mL Amber Glass Screw Cap Vial (860055P-5MG)

Other Notes

Structure, molecular formula, and molecular weight are for a representative form of the material.

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

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Ganglioside GD1a increases the excitability of voltage-dependent sodium channels
Salazar B C, et al.
Brain Research, 1021(2), 151-158 (2004)
Sialidase occurs in both membranes of the nuclear envelope and hydrolyzes endogenous GD1a
Wang J, et al.
Journal of Neurochemistry, 111(2), 547-554 (2009)
Biosynthesis of the major brain gangliosides GD1a and GT1b
Sturgill E R, et al.
Glycobiology, 22(10), 1289-1301 (2012)

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