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关于此项目
经验公式（希尔记法）:
C29H59NO2
化学文摘社编号:
分子量:
453.78
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
产品名称
N-C12-desoxymethylsphinganine, N-lauroyl-1-desoxymethylsphinganine (m17:0/12:0), powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (860461P-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 860461P
lipid type
sphingolipids
bioactive lipids
shipped in
dry ice
storage temp.
−20°C
General description
N-C12-desoxymethylsphinganine commonly referred to as 1-deoxydihydroceramide (1-deoxyDHCer), is the N-acylated form of 1-deoxysphinganine, a potent inhibitor of sphingolipid metabolism.
Commonly referred to as 1-desoxymethyldihydroceramide (1-desoxyMeDHCer), this product is the N-acylated form of 1-desoxymethylsphinganine, a potent inhibitor of sphingolipid metabolism. The biological activity of 1-desoxyMeDHCer is not clearly understood at this time.
Biochem/physiol Actions
Ceramide synthases (CerS) catalyzes the acylation of sphingoid bases using fatty acyl-CoA and its inhibition results in decrease of desoxymethylsphinganine (N-acylsphinganines (dihydroceramides)) levels and accumulation of sphinganine (Sa). Dihydroceramides (DHCer) are intermediates of ceramide biosynthesis.
Packaging
5 mL Amber Glass Screw Cap Vial (860461P-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3