产品名称
C10 bisphosphonate, Avanti Research™ - A Croda Brand 860480P, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 500 μg (860480P-500ug)
manufacturer/tradename
Avanti Research™ - A Croda Brand 860480P
lipid type
bioactive lipids
sphingolipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
[NH3+]C(P([O-])(O)=O)(P(O)(O)=O)CCCCCCCCC
InChI
1S/C10H25NO6P2/c1-2-3-4-5-6-7-8-9-10(11,18(12,13)14)19(15,16)17/h2-9,11H2,1H3,(H2,12,13,14)(H2,15,16,17)
InChI key
TWYYYYAFACTHMV-UHFFFAOYSA-N
Application
C10 bisphosphonate is suitable for use as an inhibitor for acid sphingomyelinase.
Biochem/physiol Actions
C10 bisphosphonate, with prolonged carbon chain, is an inhibitor for acid sphingomyelinase and may be a treatment option for inflammatory lung diseases, cystic fibrosis and atherosclerosis. It interacts with the divalent metal ions and forms bidentate complexes. Bisphosphonates are inhibitors of end reaction in pathways. It is an inhibitor of cytosolic farnesyl diphosphate (FDP) synthase (geranyl diphosphate (GDP) and geranylgeranyl diphosphate (GGDP) synthase and isoprene pathway. Bisphosphonates have antimicrobial functionality and inhibits the growth of Entamoeba histolytica and Plasmodium falciparum.
Packaging
5 mL Amber Glass Screw Cap Vial (860480P-500ug)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable