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Merck
CN

860561P

Avanti

18:1-12:0 Biotin PA

Avanti Research - A Croda Brand

Synonym(s):

1-oleoyl-2-(12-biotinyl(aminododecanoyl))-sn-glycero-3-phosphate (ammonium salt)

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About This Item

Empirical Formula (Hill Notation):
C43H81N4O10PS
CAS Number:
Molecular Weight:
877.16
UNSPSC Code:
12352211
NACRES:
NA.25
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Product Name

18:1-12:0 Biotin PA, Avanti Research - A Croda Brand 860561P, powder

InChI

1S/C43H78N3O10PS.H3N/c1-2-3-4-5-6-7-8-9-10-11-12-14-17-20-23-30-40(48)54-33-36(34-55-57(51,52)53)56-41(49)31-24-21-18-15-13-16-19-22-27-32-44-39(47)29-26-25-28-38-42-37(35-58-38)45-43(50)46-42;/h9-10,36-38,42H,2-8,11-35H2,1H3,(H,44,47)(H2,45,46,50)(H2,51,

InChI key

LAYLPTJRIODVKN-MMGYSICESA-N

SMILES string

[H][C@@](COP([O-])(O)=O)(OC(CCCCCCCCCCCNC(CCCC[C@]1([H])SC[C@@]2([H])[C@]1([H])NC(N2)=O)=O)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[NH4+]

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (860561P-1mg)

manufacturer/tradename

Avanti Research - A Croda Brand 860561P

shipped in

dry ice

storage temp.

−20°C

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General description

18:1-12:0 Biotin PA is a biotinylated form of phosphatidic acid, which can be immobilized on a solid support via streptavidin tether.

Application

18:1-12:0 Biotin PA is suitable for use in lipid blot analysis to study Niemann-Pick C2 (NPC2)-lipid interactions.

Packaging

5 mL Clear Glass Sealed Ampule (860561P-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

flash_point_f

No data available

flash_point_c

No data available

Regulatory Information

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Intracellular cholesterol trafficking is dependent upon NPC2 interaction with lysobisphosphatidic acid
McCauliff LA, et al.
eLife, 8 (2019)

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