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Merck
CN

860563C

Avanti

18:1-12:0 Biotin PC

Avanti Research™ - A Croda Brand

Synonym(s):

1-oleoyl-2-[12-biotinyl(aminododecanoyl)]-sn-glycero-3-phosphocholine

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About This Item

Empirical Formula (Hill Notation):
C48H89N4O10PS
CAS Number:
2260669-99-4
Molecular Weight:
945.28
UNSPSC Code:
12352211
NACRES:
NA.25

Key Documents

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Product Name

18:1-12:0 Biotin PC, Avanti Research™ - A Croda Brand 860563C

InChI key

ANVUOOKUJFVAPJ-KKWOEEAUSA-N

SMILES string

[H][C@@](COP([O-])(OCC[N+](C)(C)C)=O)(OC(CCCCCCCCCCCNC(CCCC[C@]1([H])SC[C@@]2([H])[C@]1([H])NC(N2)=O)=O)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mL (860563C-1mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 860563C

concentration

1 mg/mL (860563C-1mg)

shipped in

dry ice

storage temp.

−20°C

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Application

18:1-12:0 Biotin PC may be used in lipid blot analysis to study Niemann-Pick C2 (NPC2)-lipid interactions. It may also be used in the preparation of liposomes.

Packaging

5 mL Clear Glass Sealed Ampule (860563C-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

target_organs

Central nervous system, Liver,Kidney

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

Regulatory Information

易制毒化学品（2类）
危险化学品
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Intracellular cholesterol trafficking is dependent upon NPC2 interaction with lysobisphosphatidic acid
McCauliff LA, et al.
eLife, 8 (2019)
The Rab11-binding protein RELCH/KIAA1468 controls intracellular cholesterol distribution
Sobajima T, et al.
The Journal of Cell Biology, 217(5), 1777-1796 (2018)

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