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Merck
CN

860604P

Avanti

Phytosphingosine-N,N-Dimethyl

Avanti Research - A Croda Brand

Synonym(s):

4-hydroxysphinganine-N,N-dimethyl (Saccharomyces Cerevisiae)

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About This Item

Empirical Formula (Hill Notation):
C20H43NO3
CAS Number:
Molecular Weight:
345.56
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
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Product Name

Phytosphingosine-N,N-Dimethyl, Avanti Research - A Croda Brand, powder

InChI

1S/C20H43NO3/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-19(23)20(24)18(17-22)21(2)3/h18-20,22-24H,4-17H2,1-3H3/t18-,19+,20-/m0/s1

InChI key

OCIMVTKSHQIFRC-ZCNNSNEGSA-N

SMILES string

O[C@]([H])(CCCCCCCCCCCCCC)[C@](O)([H])[C@](N(C)C)([H])CO

assay

99% (TLC)

form

powder

packaging

1 ea of 5 mg (860604P-5mg)

manufacturer/tradename

Avanti Research - A Croda Brand

lipid type

sphingolipids

shipped in

dry ice

storage temp.

−20°C

General description

N,N-dimethyl phytosphingosine (DMPS) is a derivative of phytosphingosine.

Biochem/physiol Actions

N,N-dimethyl phytosphingosine (DMPS) prevents the conversion of sphingosine to sphingosine-1-phosphate (S1P). It is a potent anti-cancerous therapeutic agent in human leukemia cells.

Packaging

5 mL Clear Glass Sealed Ampule

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

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N, N-dimethyl phytosphingosine induces caspase-8-dependent cytochrome c release and apoptosis through ROS generation in human leukemia cells
Kim B M, et al.
Toxicology and Applied Pharmacology, 239(1), 87-97 (2009)

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