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About This Item
Empirical Formula (Hill Notation):
C24H49NO3
CAS Number:
Molecular Weight:
399.65
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
Product Name
C6 Dihydroceramide (d18:0/6:0), Avanti Research™ - A Croda Brand 860633P, powder
lipid type
sphingolipids
SMILES string
OC[C@]([H])(NC(CCCCC)=O)[C@]([H])(O)CCCCCCCCCCCCCCC
InChI
1S/C24H49NO3/c1-3-5-7-8-9-10-11-12-13-14-15-16-18-19-23(27)22(21-26)25-24(28)20-17-6-4-2/h22-23,26-27H,3-21H2,1-2H3,(H,25,28)/t22-,23+/m0/s1
InChI key
VUMHYWBWYSPQMM-XZOQPEGZSA-N
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 5 mg (860633P-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 860633P
shipped in
dry ice
storage temp.
−20°C
General description
C6 Dihydroceramide is a non-permeable, inert synthetic lipid.
Application
C6 Dihydroceramide has been used as a component of cultural media during osteoclastogenesis assay.
Packaging
5 mL Amber Glass Screw Cap Vial (860633P-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class
11 - Combustible Solids
wgk
WGK 3
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Phosphoglycerol dihydroceramide, a distinctive ceramide produced by Porphyromonas gingivalis, promotes RANKL-induced osteoclastogenesis by acting on non-muscle myosin II-A (Myh9), an osteoclast cell fusion regulatory factor
Kanzaki H, et al.
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1862(5), 452-462 (2017)
Hiroyuki Kanzaki et al.
Biochimica et biophysica acta. Molecular and cell biology of lipids, 1862(5), 452-462 (2017-02-06)
Among several virulence factors produced by the periodontal pathogen Porphyromonas gingivalis (Pg), a recently identified novel class of dihydroceramide lipids that contains a long acyl-chain has the potential to play a pathogenic role in periodontitis because of its higher level
Xianqiong Zou et al.
The Journal of biological chemistry, 286(2), 1301-1311 (2010-10-27)
Glycolipid transfer protein (GLTP) accelerates glycolipid intermembrane transfer via a unique lipid transfer/binding fold (GLTP fold) that defines the GLTP superfamily and is the prototype for functional GLTP-like domains in larger proteins, i.e. FAPP2. Human GLTP is encoded by the
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