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About This Item
Empirical Formula (Hill Notation):
C37H73NO3
CAS Number:
Molecular Weight:
579.98
UNSPSC Code:
12352100
NACRES:
NA.25
Product Name
C20 Ceramide (d17:1/20:0), Avanti Research™ - A Croda Brand 860648P, powder
Assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 10 mg (860648P-10mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 860648P
lipid type
deuterated lipids
sphingolipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
OC[C@]([H])(NC(CCCCCCCCCCCCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCC
InChI key
CZKJGFHQZINDHS-RQDJVNCUSA-N
General description
C20 Ceramide (d17:1/20:0) is a synthetic ceramide containing C17 analog of sphingosine with arachidonic acid. Ceramide synthase 2 catalyzes the synthesis of C20 Ceramide. Ceramide is the key component of sphingolipids.
Application
C20 Ceramide (d17:1/20:0) has been used as an internal standard to measure the sphingolipid content in liver by ultra-high performance liquid chromatography tandem mass spectrometry (UHPLC/MS/MS).
Biochem/physiol Actions
Ceramides play an important role in cell signaling, cell differentiation, proliferation and apoptosis.
Packaging
5 mL Amber Glass Screw Cap Vial (860648P-10mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
No data available
Flash Point(C)
No data available
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Ceramide Structure and Derivatives
Kumari A
Sweet Biochemistry: Remembering Structures, Cycles, and Pathways by Mnemonics (2018)
Luisa Coderch et al.
American journal of clinical dermatology, 4(2), 107-129 (2003-01-30)
Ceramides are the major lipid constituent of lamellar sheets present in the intercellular spaces of the stratum corneum. These lamellar sheets are thought to provide the barrier property of the epidermis. It is generally accepted that the intercellular lipid domain
Hady Razak Hady et al.
Journal of clinical medicine, 8(12) (2019-12-18)
The liver plays a central role in the glucose and lipid metabolism. Studies performed on animal models have shown an important role of lipid accumulation in the induction of insulin resistance. We sought to explain whether in obese humans, the
Ling Chen et al.
Oncology reports, 34(1), 447-454 (2015-05-16)
Endocannabinoids and ceramides have demonstrated growth inhibition, cell death induction and pro-apoptotic activity in cancer research. In the present study, we describe the profiles of two major endocannabinoids, ceramides, free fatty acids and relevant metabolic enzymes in 47 pairs of
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