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860854P

Avanti

C24:0 Galactosyl(β)ceramide(d18:1/24:0)

Avanti Research™ - A Croda Brand

Synonym(s):

D-galactosyl-β-1,1’-N-lignoceroyl-D-erythro-sphingosine

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About This Item

Empirical Formula (Hill Notation):
C48H93NO8
CAS Number:
74645-26-4
Molecular Weight:
812.25
UNSPSC Code:
12352100
NACRES:
NA.25
Assay:
99% (TLC)
Form:
powder
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Product Name

C24:0 Galactosyl(β)ceramide(d18:1/24:0), Avanti Research™ - A Croda Brand (860854P), powder

assay

99% (TLC)

form

powder

packaging

pkg of 1 × 5 mg (860854P-5MG)

manufacturer/tradename

Avanti Research™ - A Croda Brand (860854P)

lipid type

deuterated lipids
sphingolipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCCCCCCCCCCCC)=O)CO[C@H](O1)[C@H](O)[C@@H](O)[C@H]([C@H]1CO)O

InChI

1S/C48H93NO8/c1-3-5-7-9-11-13-15-17-18-19-20-21-22-23-24-26-28-30-32-34-36-38-44(52)49-41(40-56-48-47(55)46(54)45(53)43(39-50)57-48)42(51)37-35-33-31-29-27-25-16-14-12-10-8-6-4-2/h35,37,41-43,45-48,50-51,53-55H,3-34,36,38-40H2,1-2H3,(H,49,52)/b37-35+/t41-

InChI key

POQRWMRXUOPCLD-HIIAJUEOSA-N

General description

β-Galactosyl ceramide (β-GalCer) is a simple glycosphingolipid. It is made up of lipophilic sphingosine & hydrophilic galactose attached to sphingosine via ether linkage. Β-GalCer is present in the myelin sheath of the central and peripheral nervous system. It has five analogs including 6a-6e.

Biochem/physiol Actions

β-Galactosyl ceramide (β-GalCer) regulates the activity of β-glucocerebrosidase. It also plays a role as cell surface receptors for bacterial and viral toxins.

Packaging

5 mL Amber Glass Screw Cap Vial

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

涉药品监管产品

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Design, synthesis, and evaluation of beta-galactosylceramide mimics promoting beta-glucocerebrosidase activity in keratinocytes
Fukunaga K, et al.
Bioorganic & Medicinal Chemistry Letters, 13(5), 813-815 (2003)