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Merck
CN

870336C

Avanti

Soy PS

Avanti Research™ - A Croda Brand

Synonym(s):

L-α-phosphatidylserine (Soy, 99%) (sodium salt)

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About This Item

CAS Number:
383908-63-2
UNSPSC Code:
12352211
NACRES:
NA.25

Key Documents

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Product Name

Soy PS, Avanti Research™ - A Croda Brand 870336C

SMILES string

[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]

InChI

1S/C40H74NO10P.Na/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-39(43)51-36(34-49-52(46,47)50-35-37(41)40(44)45)33-48-38(42)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2;/h11,13,17-18,36-37H,3-10,12,14-16,19-35,41H2,1-2H3,(H,44,45)(H,46,47);/q;+1/p-1/b13-11-,18-17-;/t36-,37+;/m1./s1

InChI key

WPLLCKLCLMRAPV-WHVRKWPVSA-M

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (870336C-25mg)
pkg of 2 × 4 mL (870336C-200mg)
pkg of 5 × 4 mL (870336C-500mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 870336C

concentration

10 mg/mL (870336C-25mg)
25 mg/mL (870336C-200mg)
25 mg/mL (870336C-500mg)

lipid type

phosphoglycerides

shipped in

dry ice

storage temp.

−20°C

Application

Soy PS is suitable for use:
  • as standard and in the preparation of calibration curve for liquid chromatography-tandem mass spectrometry (LC-MS/MS)
  • in the preparation of lipid bilayer disks
  • as a substrate to determine the interaction of anionic lipids with Clostridium sordellii lethal toxin-N terminal catalytic domain (TcsL-cat)
  • in the preparation of liposomes mimicking the inner mitochondrial membrane

Biochem/physiol Actions

Phosphatidylserine (PS) is mainly present in the cytosolic leaflet of plasma membrane, endosomes and lysosomes. It is also present in the interior of the endoplasmic reticulum, Golgi complex and mitochondria. PS is the preferential binding substrate for Clostridium sordellii lethal toxin (TcsL). PS is a component of the lipid-calcium-phosphate complex for deposition during bone formation, regulation of apoptosis and blood coagulation.

General description

Phosphatidylserine (PS) is one of the major phospholipids in biological tissues and food samples. PS has unsaturated acyl chains in their structure.

Packaging

5 mL Clear Glass Sealed Ampule (870336C-200mg)
5 mL Clear Glass Sealed Ampule (870336C-25mg)
5 mL Clear Glass Sealed Ampule (870336C-500mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

target_organs

Liver,Kidney, Respiratory system

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash

Regulatory Information

危险化学品
易制毒化学品（2类）
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Evaluation of bilayer disks as plant cell membrane models in partition studies
Boija E, et al.
Analytical biochemistry, 364(2), 145-152 (2007)
Validation of an LC-MS/MS method for the quantification of choline-related compounds and phospholipids in foods and tissues
Xiong Y, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 911, 170-179 (2012)
Effect of ubiquinone-10 on the stability of biomimetic membranes of relevance for the inner mitochondrial membrane
Eriksson EK, et al.
Biochimica et Biophysica Acta - Biomembranes, 1860(5), 1205-1215 (2018)
The use of natural and synthetic phospholipids as pharmaceutical excipients
van Hoogevest P and Wendel A
European Journal of Lipid Science and Technology, 116(9), 1088-1107 (2014)
The catalytic domains of Clostridium sordellii lethal toxin and related large clostridial glucosylating toxins specifically recognize the negatively charged phospholipids phosphatidylserine and phosphatidic acid
Varela Chavez C, et al.
Cellular Microbiology, 17(10), 1477-1493 (2015)
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