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Merck
CN

880001O

Avanti

Chol-PEG600

Avanti Research™ - A Croda Brand

Synonym(s):

Cholesterol-(polyethylene glycol-600)

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About This Item

CAS Number:
27321-96-6
UNSPSC Code:
12352211
NACRES:
NA.25

Key Documents

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Product Name

Chol-PEG600, Avanti Research™ - A Croda Brand 880001O

SMILES string

[H][C@@]12[C@]([C@](CC[C@H](OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO)C3)(C)C3=CC2)([H])CC[C@@]4(C)[C@@]1([H])CC[C@]4([H])[C@]([H])(C)CCCC(C)C

InChI

1S/C29H50O2/c1-20(2)7-6-8-21(3)25-11-12-26-24-10-9-22-19-23(31-18-17-30)13-15-28(22,4)27(24)14-16-29(25,26)5/h9,20-21,23-27,30H,6-8,10-19H2,1-5H3

InChI key

NPYXBHZQVNRAOF-UHFFFAOYSA-N

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 25 mg (880001O-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 880001O

shipped in

dry ice

storage temp.

−20°C

Biochem/physiol Actions

PEG-cholesterol is widely used for cationic DNA transfection studies, and preparation of liposomes for encapsulated drug delivery.

General description

Cholesterol-(polyethylene glycol-600) (Chol-PEG600) is a nonionic amphipathic lipid and a cholesterol derivative. It is a water soluble, non-homogeneous compound containing hydrophobic cholesterol and covalently bound hydrophilic PEG.

Packaging

5 mL Clear Glass Sealed Ampule (880001O-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

10 - Combustible liquids

wgk

WGK 3

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Certificates of Analysis (COA)

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Poly (ethylene glycol)-cholesterol inhibits L-type Ca2+ channel currents and augments voltage-dependent inactivation in A7r5 cells
Ochi, R, et al.
PLoS ONE, 9(9) (2014)
Poly (ethylene glycol)-cholesterol inhibits L-type Ca2+ channel currents and augments voltage-dependent inactivation in A7r5 cells
Ochi, R, et al.
Testing, 9(9) (2014)
Rikuo Ochi et al.
PloS one, 9(9), e107049-e107049 (2014-09-10)
Cholesterol distributes at a high density in the membrane lipid raft and modulates ion channel currents. Poly(ethylene glycol) cholesteryl ether (PEG-cholesterol) is a nonionic amphipathic lipid consisting of lipophilic cholesterol and covalently bound hydrophilic PEG. PEG-cholesterol is used to formulate
CHOBIMALT: a cholesterol-based detergent
Howell S, et al.
Biochemistry, 49(44), 9572-9583 (2010)

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