登录 查看组织和合同定价。
选择规格
变更视图
关于此项目
经验公式(希尔记法):
C94H147NO42
化学文摘社编号:
分子量:
1963.15
UNSPSC Code:
12352211
MDL number:
NACRES:
NA.28
assay
≥99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (890813P-1MG), pkg of 1 × 5 mg (890813P-5MG)
manufacturer/tradename
Avanti Research™ - A Croda Brand
solubility
DMSO: soluble (1mg in 50uL of DMSO turns clear.)
application(s)
vaccine development
shipped in
dry ice
storage temp.
−20°C
General description
VSA-2 is a semisynthetic saponin adjuvant derived from the naturally available Momordica saponin, designed to stimulate antigen-specific humoral and cellular immune responses. It is created by adding a terminal-functionalized side chain to the branched trisaccharide domain at the C3 position of Momordica saponin II (MS II), which is extracted from the seeds of Momordica cochinchinensis Spreng. When compared directly to the clinically validated saponin adjuvant QS-21, VSA-2 demonstrates comparable effectiveness in enhancing both humoral and cellular immune responses.
Application
Vaccine development
Features and Benefits
VSA-2 demonstrates the ability to improve antibody and T-cell responses in murine models across multiple antigen classes, including PCV13-based conjugate vaccines. Its compatibility with mRNA, protein, and polysaccharide vaccine formats enables it to serve as a reliable alternative to QS-21.
Packaging
5 mL Amber Glass Screw Cap Vial (890813P-1MG); 5 mL Amber Glass Screw Cap Vial (890813P-5MG)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable