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About This Item
Empirical Formula (Hill Notation):
C42H84NO4Cl
CAS Number:
Molecular Weight:
702.57
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 200 mg (890880P-200mg), pkg of 1 × 25 mg (890880P-25mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
lipid type
cationic lipids
transfection
shipped in
dry ice
storage temp.
−20°C
SMILES string
[H]C(C[N+](C)(C)C)(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.[Cl-]
InChI key
NTTZBBIBMSBLNK-UHFFFAOYSA-M
Application
1,2-stearoyl-3-trimethylammonium-propane (18:0 TAP) might be used:
- for the preparation of tri-loaded bilosomes (Tri-BLs) by thin film hydration technique
- to formulate lipid nanoparticles (LNPs), for testing its efficiency of packaging mRNA into an LNP
- to fabricate unilamellar empty liposomes
- to prepare lipoplexes
Biochem/physiol Actions
1,2-stearoyl-3-trimethylammonium-propane (18:0 TAP) is a cationic lipid used in DNA transfection.
Packaging
5 mL Amber Glass Screw Cap Vial (890880P-200mg)
5 mL Amber Glass Screw Cap Vial (890880P-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
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Storage Class
11 - Combustible Solids
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Hailing Yang et al.
Drug delivery, 26(1), 820-830 (2019-08-08)
Arthritis treatment has been challenging because of low drug exposure to the articular cavity. This study was intended to develop hyaluronic acid (HA)-functionalized bilosomes for targeted delivery of tripterine (Tri), an antiphlogistic phytomedicine, to the inflamed joint via ligand-receptor interaction.
Zhiqiang Sun et al.
Biomacromolecules, 13(10), 3395-3400 (2012-09-20)
Lipid-coated DNA nanoparticles (lipoplexes) are a powerful gene delivery tool with promising therapeutic applications. The mechanism of lipoplex assembly remains poorly understood. We explored DNA packing by a cationic lipid DSTAP (distearoyl trimethylammonium-propane) using magnetic tweezers. DSTAP-induced DNA condensation occurred
Maria Jose York-Duran et al.
Biomaterials science, 7(11), 4813-4826 (2019-09-20)
While ROS display crucial functions in many physiological processes, elevated ROS levels are also related to the initiation and progression of many severe diseases such as cancer, cardiovascular conditions or neurologic disorders. Research approaches to diminish ROS levels during disease
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 890880P-25MG | 04061835188505 |
| 890880P-200MG | 04061835188499 |