Product Name
Polyprenol (13~21), Avanti Research™ - A Croda Brand 900210O
InChI key
YHTCXUSSQJMLQD-PSTDWBAXSA-N
SMILES string
CC(C)=CCC/C(C)=C/CC/C(C)=C/CC/C(C)=C\CC/C(C)=C\CO
assay
>99% (TLC)
form
liquid
packaging
pkg of 1 × 1 mg (900210O-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 900210O
lipid type
neutral glycerides
shipped in
dry ice
storage temp.
−20°C
Biochem/physiol Actions
Polyprenols can be predominantly used as a natural bioregulators. Dolichol concentration in animal tissues increases with age. Therefore, it can be used as a potential biomarker of aging. Increased serum dolichol levels leads to the development of chronic cholestatic liver diseases.
General description
Polyprenols or poly-isoprene-ols are primary monohydric alcohols containing 5 to 25 isoprene units in its carbon skeleton, with a hydroxyl group placed at the end. They are found in limited quantities in several plant tissues. Dolichol is an α-saturated polyisoprenoid alcohol with 13-21 isoprene units. Dolichol found in yeast and fungi, facilitate the synthesis of mannoproteins.
Packaging
5 mL Clear Glass Sealed Ampule (900210O-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class
10 - Combustible liquids
wgk
WGK 3
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Carbohydrates Volume 2 of Methods in Plant Biochemistry (2012)
Accumulation of dolichol in older tissues satisfies the proposed criteria to be qualified a biomarker of aging
Parentini I, et al.
The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences, 60(1), 39-43 (2005)
Biochemistry of Lipids: Biochemistry Series One, 4 (2014)
Chromatography of long chain alcohols (polyprenols) from animal and plant sources
Rezanka T and Votruba J
Journal of Chromatography A, 936(1-2), 95-110 (2001)
Biology and Chemistry of Eukaryotic Cell Surfaces, 7(1) (2012)
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