LM6003
Avanti
Cardiolipin Mix I
Avanti Research™ - A Croda Brand
Synonym(s):
Cardiolipin Mix I, Cardiolipin Mixture Internal Standard
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About This Item
UNSPSC Code:
41116107
NACRES:
NA.25
Assay
>99% (TLC)
form
methanol solution
packaging
pkg of 1 × 1 mL (LM6003-1EA)
manufacturer/tradename
Avanti Research™ - A Croda Brand
concentration
~100 μg/mL (Refer to C of A for lot specific concentration. )
application(s)
lipidomics
metabolomics
shipped in
dry ice
storage temp.
−20°C
General description
Cardiolipin is an anionic phospholipid located in the inner mitochondrial membrane. It constitutes 20% of total lipids. The non-bilayer has four acyl chains and a small head group.
Application
Cardiolipin Mix I has been used as an internal standard in the mass-spectrometric analysis of phospholipids.
Biochem/physiol Actions
Cardiolipin plays a vital role in the organization of membranes and cell division. It regulates the proton uptake pathway. It contributes to mitochondrial biogenesis, fusion and fission, respiration and protein import. Cardiolipin controls cell wall biogenesis, vacuole homeostasis, aging, cell cycle and apoptosis.
Packaging
2 mL Amber Glass Sealed Ampule (LM6003-1EA)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
Target Organs
Eyes
Storage Class Code
3 - Flammable liquids
WGK
WGK 2
Flash Point(F)
49.5 °F - closed cup
Flash Point(C)
9.7 °C - closed cup
Regulatory Information
危险化学品
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Structural insight into the TRIAP1/PRELI-like domain family of mitochondrial phospholipid transfer complexes
Miliara X, et al.
EMBO Reports, 16(7), 824-835 (2015)
The role of cardiolipin in cardiovascular health
Shen Z, et al.
BioMed Research International, 2015 (2015)
Acylglycerol kinase mutated in Sengers syndrome is a subunit of the TIM22 protein translocase in mitochondria
Vukotic M, et al.
Molecular Cell, 67(3), 471-483 (2017)
MICOS and phospholipid transfer by Ups2--Mdm35 organize membrane lipid synthesis in mitochondria
Aaltonen MJ, et al.
The Journal of Cell Biology, 213(5), 525-534 (2016)
Role of cardiolipin in mitochondrial signaling pathways
Dudek J
Frontiers in Cell and Developmental Biology, 5, 90-90 (2017)
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