03-0203-00
SMC® Human GFAP High Sensitivity Immunoassay Kit
Used for ultrasensitive quantification of Human GFAP in human serum, plasma, and cerebrospinal fluid (CSF)
Synonym(s):
GFAP Single Molecule Counting Kit, GFAP ultra-sensitive immunoassay, Glial fibrillary acidic protein immunoassay kit
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About This Item
General description
GFAP serves as an important biomarker for astrocyte activation and neuroinflammation. Elevated levels of GFAP in cerebrospinal fluid (CSF) and blood may indicate reactive astrogliosis, a condition often associated with brain injury, multiple sclerosis, Alzheimer′s disease, and other neurodegenerative disorders. As increased GFAP levels often reflect the extent of neuroinflammatory responses and neuronal damage, GFAP is a critical target to monitor when developing strategies aimed at mitigating neuroinflammation and preserving neuronal health.
Application
Features and Benefits
- Femtogram-Level Aβ1-42 Detection: Achieves exceptional sensitivity (fg/mL) in serum, plasma or CSF.
- Enhanced Signal Performance: Features a broadened dynamic range with reduced background noise, ensuring consistent results.
- Familiar Assay Format: Utilizes a standard sandwich immunoassay design merged with advanced sensitivity.
- Flexible Automation Integration: Incorporates with liquid handling systems to standardize workflows and further minimize variability.
- Specialized Technical Support: Supported by SMC® platform experts.
Packaging
Analysis Note
- Sensitivity: LLOQ 230 fg/mL* (SMCxPRO® Instrument)
- Standard Curve Range: 60-300,000 fg/mL
- Intra-assay CV: <15%
- Inter-assay CV: <20%
- Linearity: Serum: 101% Plasma: 99% CSF: 101%
- Recovery: Serum: 118% Plasma: 115% CSF: 101%
Other Notes
Legal Information
Disclaimer
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Danger
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - ED ENV 1 - Eye Irrit. 2 - Repr. 1B
Regulatory Information
Certificates of Analysis (COA)
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