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Merck
CN

05-23-2150

PACAP 38, Ovine

More active than vasoactive intestinal peptide (VIP) in stimulating adenylate cyclase (EC50 = 7 nM).

Synonym(s):

PACAP 38, Ovine, Pituitary Adenylate Cyclase Activating Polypeptide, HSDGIFTDSYSRYRKQMAVKKYLAAVLGKRYKQRVKNK-NH2

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About This Item

Empirical Formula (Hill Notation):
C203H331N63O53S
CAS Number:
137061-48-4
Molecular Weight:
4534.26
UNSPSC Code:
12352202
NACRES:
NA.77
MDL number:
MFCD00081800

Key Documents

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Product Name

PACAP 38, Ovine, More active than vasoactive intestinal peptide (VIP) in stimulating adenylate cyclase (EC50 = 7 nM).

assay

≥96% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
desiccated (hygroscopic)

color

white to off-white

solubility

5% acetic acid: 1 mg/mL

shipped in

ambient

storage temp.

−20°C

Quality Level

100

Biochem/physiol Actions

Cell permeable: no
EC50 = 7 nM against adenylate cyclase
Primary Target
Adenylate cyclase
Product does not compete with ATP.
Reversible: no

Disclaimer

Toxicity: Standard Handling (A)

General description

More active than vasoactive intestinal peptide (VIP) in stimulating adenylate cyclase (EC50 = 7 nM).

Other Notes

H-His-Ser-Asp-Gly-Ile-Phe-Thr-Asp-Ser-Tyr-Ser-Arg-Tyr-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Ala-Ala-Val-Leu-Gly-Lys-Arg-Tyr-Lys-Gln-Arg-Val-Lys-Asn-Lys-NH₂
Kobayashi, H., et al. 1994. Brain Res.647, 145.
Chastre, E., et al. 1991. J. Biol. Chem.266, 21239.
Le Meuth, V., et al. 1991. Am. J. Physiol. 260, G265.
Kimura, C., et al. 1990. Biochem. Biophys. Res. Commun.166, 81.

Packaging

Yes

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

监管及禁止进口产品
This item has

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