218742
Caspase Inhibitor I, Biotin Conjugate
The Caspase Inhibitor I, Biotin Conjugate controls the biological activity of Caspase. This small molecule/inhibitor is primarily used for Cancer applications.
Synonym(s):
Caspase Inhibitor I, Biotin Conjugate, Biotin-X-VAD-FMK
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About This Item
Empirical Formula (Hill Notation):
C30H49FN6O8S
Molecular Weight:
672.81
UNSPSC Code:
12352200
NACRES:
NA.54
Quality Level
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
desiccated
color
brown
solubility
DMSO: 20 mM
shipped in
ambient
storage temp.
−20°C
General description
Biotinylated derivative of Caspase Inhibitor I (Cat. No. 627610) that may be used to identify active caspases in cell lysates.
Biochem/physiol Actions
Cell permeable: no
Primary Target
Caspase
Caspase
Product does not compete with ATP.
Reversible: no
Warning
Toxicity: Standard Handling (A)
Sequence
Biotin-X-Val-Ala-Asp(OMe)-CH₂F* (X = linker)
Reconstitution
Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Analysis Note
single spot by TLC
Other Notes
Li, S. et al. 1999. J. Biol. Chem.274, 17325.
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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