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Merck
CN

480703-M

Millipore

Neurodazine

A cell-permeable trisubstituted imidazole compound that induces neurogenesis of non-pluripotent C2C12 myoblasts as well as cells derived from mature human skeletal muscle cultures (2 µM for 7-10 days).

Synonym(s):

Neurodazine, 2-(2-(5-(3-Chlorophenyl))furanyl)-4,5-bis-(4-methoxyphenyl)-imidazole, Nz

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About This Item

Empirical Formula (Hill Notation):
C27H21ClN2O3
CAS Number:
Molecular Weight:
456.92
MDL number:
UNSPSC Code:
12352200
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Assay

≥98% (HPLC)

form

film

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
protect from light

color

yellow

solubility

DMSO: 10 mg/mL
ethanol: 5 mg/mL

storage temp.

2-8°C

InChI

1S/C27H21ClN2O3/c1-31-21-10-6-17(7-11-21)25-26(18-8-12-22(32-2)13-9-18)30-27(29-25)24-15-14-23(33-24)19-4-3-5-20(28)16-19/h3-16H,1-2H3,(H,29,30)

InChI key

FEEOFPAEDSMOTO-UHFFFAOYSA-N

General description

A cell-permeable trisubstituted imidazole compound that induces neurogenesis of non-pluripotent C2C12 myoblasts as well as cells derived from mature human skeletal muscle cultures (2 µM for 7-10 days). Shown to preferentially upregulate genes involved in neurogenesis, but not those pertaining to myogenesis, in C2C12 myoblasts.

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Other Notes

Williams, D.R., et al. 2007. J. Am. Chem. Soc.129, 9258.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

668.8 °F

Flash Point(C)

353.8 °C


Certificates of Analysis (COA)

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