480703-M
Neurodazine
A cell-permeable trisubstituted imidazole compound that induces neurogenesis of non-pluripotent C2C12 myoblasts as well as cells derived from mature human skeletal muscle cultures (2 µM for 7-10 days).
Synonym(s):
Neurodazine, 2-(2-(5-(3-Chlorophenyl))furanyl)-4,5-bis-(4-methoxyphenyl)-imidazole, Nz
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About This Item
Empirical Formula (Hill Notation):
C27H21ClN2O3
CAS Number:
Molecular Weight:
456.92
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
film
Storage condition:
OK to freeze, protect from light
assay
≥98% (HPLC)
form
film
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, protect from light
color
yellow
solubility
DMSO: 10 mg/mL, ethanol: 5 mg/mL
storage temp.
2-8°C
InChI
1S/C27H21ClN2O3/c1-31-21-10-6-17(7-11-21)25-26(18-8-12-22(32-2)13-9-18)30-27(29-25)24-15-14-23(33-24)19-4-3-5-20(28)16-19/h3-16H,1-2H3,(H,29,30)
InChI key
FEEOFPAEDSMOTO-UHFFFAOYSA-N
General description
A cell-permeable trisubstituted imidazole compound that induces neurogenesis of non-pluripotent C2C12 myoblasts as well as cells derived from mature human skeletal muscle cultures (2 µM for 7-10 days). Shown to preferentially upregulate genes involved in neurogenesis, but not those pertaining to myogenesis, in C2C12 myoblasts.
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Other Notes
Williams, D.R., et al. 2007. J. Am. Chem. Soc.129, 9258.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
668.8 °F
flash_point_c
353.8 °C
Certificates of Analysis (COA)
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