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Merck
CN

48-625MAG

MILLIPLEX® Phospo/Total mTOR Signaling Panel

Premixed mTOR Phospo/Total 2-Plex Cell Signaling Panel

Synonym(s):

PI3K/mTOR pathway, mTOR ELISA, mTOR assay, mTOR kinase assay, mTOR multiplex panel, mTOR phosphorylation, mTOR signaling, mammalian target of rapamycin, total mTOR

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About This Item

NACRES:
NA.47
UNSPSC Code:
12161503
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Quality Level

species reactivity

human, rat, mouse

technique(s)

multiplexing: suitable

input

cell lysate

packaging

pkg of 1 ea

manufacturer/tradename

Milliplex®

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

General description

mTOR is a serine/threonine kinase that integrates signals from nutrients, growth factors, and energy status to regulate cell growth and metabolism. Phosphorylation at Ser2448 reflects mTOR activation and its role in protein synthesis and autophagy.

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze 2 analytes in human, mouse, or rat cell lysate samples.

Analytes Included: mTOR (Phospho-Ser2448), mTOR (Total)

Assay Characteristics: Refer to the assay protocol for details on cross-reactivity, buffer compatibility, lysate control, and recommended loading control (MAPmate Control Assays).

Features and Benefits

  • Quantifies both phospho and total mTOR in a single reaction
  • Enables analysis of mTOR pathway activity in cancer and metabolic research
  • High sensitivity for low-abundance targets
  • Efficient use of precious samples with multiplexing capability

Legal Information

Luminex is a registered trademark of Luminex Corp
MAPMATE is a trademark of Merck KGaA, Darmstadt, Germany
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

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Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - ED ENV 1 - Eye Dam. 1 - Skin Irrit. 2

Storage Class

10 - Combustible liquids

wgk

WGK 3

Regulatory Information

新产品
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Certificates of Analysis (COA)

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Related Content

Uncover how cells communicate with MILLIPLEX® cell signaling multiplex assays. Multiplexing with cell signaling phosphoprotein assays based on Luminex® xMAP® technology helps researchers measure phosphoproteins and total proteins within the same or different pathways from a single sample.

"Cancer research giving you mixed signals? Signaling molecules are deeply embedded in processes associated with cancer. The study of signaling pathways is nearly synonymous with cancer research. Elucidating the various cellular and molecular mechanisms of cancer requires high quality research tools that give you precise, reproducible data. At EMD Millipore, our scientists are dedicated to developing and delivering thoroughly tested and validated tools for life science research."

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