5.09886
Myristoylated Myr-KFEEERARAKWDT, mP13
别名:
Myristoylated Myr-KFEEERARAKWDT, mP13, Integrin Signaling inhibitor II, mP13
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关于此项目
经验公式（希尔记法）:
C87H138N22O24
分子量:
1876.16
UNSPSC Code:
12352200
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
OK to freeze, desiccated (hygroscopic), protect from light
assay
≥98% (HPLC)
Quality Segment
form
powder
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, desiccated (hygroscopic), protect from light
color
white
solubility
DMSO: 100 mg/mL, water: insoluble
storage temp.
−70°C
General description
A cell-permeable, myristoylated 13-mer peptide derived from EXE-motif-containing integrin β3 subunit that inhibits talin association with β3. Shown to inhibit both inside-out and outside-in signaling. Blocks all phases of integrin signaling including fibrinogen binding, platelet adhesion, and clot retraction.
Please note that the molecular weight for this compound is batch-specific due to variable water content.
Please note that the molecular weight for this compound is batch-specific due to variable water content.
Biochem/physiol Actions
Cell permeable: yes
Primary Target
Integrin alphaIIbbeta3
Integrin alphaIIbbeta3
Reversible: yes
Packaging
Packaged under inert gas
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Other Notes
KFEEERARAKWDT
Shen, B., et al. 2013. Nature503, 131.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable