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567051-M

Sinefungin

Name: Sinefungin
Brand: MM

InSolution, ≥95%, antibiotic

Synonym(s):

InSolution Sinefungin, SF, Adenosyl-ornithine, A9145

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About This Item

Empirical Formula (Hill Notation):

C₁₅H₂₃N₇O₅

CAS Number:

58944-73-3

Molecular Weight:

381.39

MDL number:

MFCD00865623

UNSPSC Code:

12352200

NACRES:

NA.77

Assay:

≥95% (HPLC)

Form:

liquid

Quality level:

100

Storage condition:

OK to freeze, protect from light

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Properties

Quality Level

100

assay

≥95% (HPLC)

form

liquid

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze, protect from light

storage temp.

−20°C

SMILES string

[n]2(c3ncnc(c3nc2)N)[C@@H]1O[C@@H]([C@H]([C@H]1O)O)C[C@@H](N)CC[C@H](N)C(=O)O

InChI

1S/C15H23N7O5/c16-6(1-2-7(17)15(25)26)3-8-10(23)11(24)14(27-8)22-5-21-9-12(18)19-4-20-13(9)22/h4-8,10-11,14,23-24H,1-3,16-17H2,(H,25,26)(H2,18,19,20)/t6-,7-,8+,10+,11+,14+/m0/s1

InChI key

LMXOHSDXUQEUSF-YECHIGJVSA-N

Description

General description

An anti-leishmanial nucleoside antibiotic that acts as an S-adenosyl-L-methionine (SAM, AdoMet) methyltransferase-specific inhibitor.

Biochem/physiol Actions

Primary Target
S-adenosyl-L-methionine (SAM, AdoMet) methyltransferase

Physical form

A 10 mM (2 mg/524 µl) solution in H₂O.

Preparation Note

Following initial thaw, aliquot and freeze (-20°C).

Other Notes

Cheng, D., et al. 2004. J. Biol. Chem.279, 23892.
Lin, Q., et al. 2001. J. Am. Chem. Soc.123, 11608.
Zingg, J.M., et al. 1996. Nucleic Acids Res.24, 3267.
McCammon, M.T., and Parks, L.W. 1981. J. Bacteriol.145, 106.
Pugh, C.S.G., et al. 1978. J. Biol. Chem.253, 4075.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

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Storage Class

11 - Combustible Solids

wgk

WGK 3

Regulatory Information

涉药品监管产品

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Global Trade Item Number

SKU	GTIN
567051-2MG	04055977267143