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Merck
CN

ABS92

Sigma-Aldrich

Anti-TNK1 Antibody

from rabbit

Synonym(s):

Non-receptor tyrosine-protein kinase TNK1, CD38 negative kinase 1

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Key Documents

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biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

purified antibody

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human

technique(s)

western blot: suitable

NCBI accession no.

NP_003976

UniProt accession no.

Q13470

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... TNK1(8711)

General description

TNK1 (thirty-eight-negative kinase 1) is a non-receptor tyrosine kinase that is widely used in fetal development signaling and more narrowly used in adult tissues and lymphohematopoietic system cells. TNK1 seems to have regulatory ability on whether TNFalpha activates NF-kappaB or apoptosis. TNK1 can also inhibit Ras function and tumor growth. Mice with a TNK1 deficiency often show unprompted tumor growth, including lymphomas and carcinomas. TNK1 downregulation has also been shown in a large number of humans with diffuse large B-cell lymphoma.
~72 kDa observed

Immunogen

KLH-conjugated linear peptide corresponding to human TNK1.

Application

Detect TNK1 using this Anti-TNK1 Antibody validated for use in WB.

Physical form

Format: Purified

Analysis Note

Evaluated by Western Blot in HeLa cell lysate.

Western Blot Analysis: 0.5 µg/mL of this antibody detected TNK1 on 10 µg of HeLa cell lysate.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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